Gene: PKIG
Official Full Name: cAMP-dependent protein kinase inhibitor gammaprovided by HGNC
Gene Summary: This gene encodes a member of the protein kinase inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive cAMP-dependent protein kinase inhibitor, and is a predominant form of inhibitor in various tissues. The encoded protein may be involved in osteogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31173 | PKIG Knockout cell line (HeLa) | Human | PKIG | 1:3~1:6 | Negative | Online Inquiry |
KO31174 | PKIG Knockout cell line (HCT 116) | Human | PKIG | 1:2~1:4 | Negative | Online Inquiry |
KO31175 | PKIG Knockout cell line (HEK293) | Human | PKIG | 1:3~1:6 | Negative | Online Inquiry |
KO31176 | PKIG Knockout cell line (A549) | Human | PKIG | 1:3~1:4 | Negative | Online Inquiry |
PKIG Gene Knockout Cell Lines are genetically modified cell lines specifically designed to lack the expression of the PKIG (Protein Kinase A Inhibitor Gamma) gene. This knockout serves as a powerful tool for researchers investigating the roles of PKIG in various biological processes, including cellular signaling, metabolism, and the regulation of gene expression. The targeted ablation of PKIG allows for a clear examination of its functional consequences in cellular models, shedding light on its involvement in health and disease.
The remarkable functionality of PKIG Gene Knockout Cell Lines stems from their ability to aid in the elucidation of the pathways dependent on Protein Kinase A (PKA) activity. By removing PKIG, which inhibits PKA signaling, researchers can investigate the resultant hyperactivation of PKA pathways, exploring potential links to tumorigenesis, cardiac function, and neurobiological disorders. This product not only serves as a valuable resource in basic research but also paves the way for innovative therapeutic strategies by providing insights into PKIG's role as a negative regulator of PKA signaling.
In comparison to alternative knockout models, PKIG Gene Knockout Cell Lines offer several advantages. They are developed using state-of-the-art CRISPR/Cas9 technology, ensuring high specificity and efficiency in gene editing. Furthermore, they are available in various cell types, accommodating diverse experimental designs and allowing the application of these cell lines across different research fields. The flexibility of these cell lines enhances their applicability in both in vitro studies and drug discovery, making them a preferred choice for many researchers.
The ability to investigate the complex functions and regulatory mechanisms of PKIG holds significant value in both research and clinical settings. By utilizing these cell lines, scientists can deploy advanced clinical assays and explore novel pharmacological interventions targeting PKIG signaling. This has far-reaching implications not only in understanding disease mechanisms but also in the development of precision medicine approaches for disorders linked to dysfunctional PKA pathways.
As leaders in the field of genetic modification and biochemical research, our company brings exceptional expertise and innovation in developing biological products like the PKIG Gene Knockout Cell Lines. Our commitment to quality and scientific advancement ensures that researchers and clinicians have access to the most reliable tools for their experimental needs.
Please note that all services are for research use only. Not intended for any clinical use.
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