Gene: PITPNM1
Official Full Name: phosphatidylinositol transfer protein membrane associated 1provided by HGNC
Gene Summary: PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005 [PubMed 15627748]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33059 | PITPNM1 Knockout cell line (HeLa) | Human | PITPNM1 | 1:3~1:6 | Negative | Online Inquiry |
KO33060 | PITPNM1 Knockout cell line (HCT 116) | Human | PITPNM1 | 1:2~1:4 | Negative | Online Inquiry |
KO33061 | PITPNM1 Knockout cell line (HEK293) | Human | PITPNM1 | 1:3~1:6 | Negative | Online Inquiry |
KO33062 | PITPNM1 Knockout cell line (A549) | Human | PITPNM1 | 1:3~1:4 | Negative | Online Inquiry |
PITPNM1 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the phosphatidylinositol transfer protein membrane-associated 1 (PITPNM1), which plays a pivotal role in phospholipid metabolism and cellular signaling pathways. These cell lines are engineered to have disrupted expression of the PITPNM1 gene, thus allowing researchers to investigate the downstream effects of its absence on various biological processes, including membrane dynamics, cellular proliferation, and signal transduction.
Functional studies utilizing PITPNM1 knockout cell lines reveal mechanisms that elucidate the relationship between PITPNM1 and key cellular processes such as lipid metabolism and membrane trafficking. By observing phenotypic changes in these knockout models, scientists can identify specific roles of PITPNM1 in pathophysiological conditions, making them indispensable in disease research, especially for cancer and neurodegenerative disorders.
The scientific importance of PITPNM1 Gene Knockout Cell Lines is underscored by their versatile applications in both basic and applied research settings. They can be utilized for drug discovery, provided insights into gene function and regulation, and facilitate the understanding of metabolic diseases related to phosphoinositide signaling. Compared to other knockout models, PITPNM1 lines offer increased specificity in targeting lipid-related pathways and can enhance the resolution of studies focusing on cellular membrane interactions.
One of the primary advantages of these cell lines is the ability for researchers to isolate and study the direct effects of PITPNM1 loss, providing a clear picture of its biological impact. Moreover, these cell lines are optimized for high reproducibility and compatibility with various assays, making them a practical choice for laboratories looking to push the boundaries of lipid signaling research.
In conclusion, PITPNM1 Gene Knockout Cell Lines represent a significant advancement in cellular research tools, combining specificity and versatility. Our company is committed to delivering high-quality biological products backed by extensive expertise in genetic modifications and cell line development, ensuring that researchers have the best resources at their fingertips to advance their scientific inquiries.
Please note that all services are for research use only. Not intended for any clinical use.
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