Gene: PITPNA
Official Full Name: phosphatidylinositol transfer protein alphaprovided by HGNC
Gene Summary: This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3) by phosphoinositide-3-kinase.[provided by RefSeq, Sep 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36067 | PITPNA Knockout cell line (HeLa) | Human | PITPNA | 1:3~1:6 | Negative | Online Inquiry |
KO36068 | PITPNA Knockout cell line (HCT 116) | Human | PITPNA | 1:2~1:4 | Negative | Online Inquiry |
KO36069 | PITPNA Knockout cell line (HEK293) | Human | PITPNA | 1:3~1:6 | Negative | Online Inquiry |
KO36070 | PITPNA Knockout cell line (A549) | Human | PITPNA | 1:3~1:4 | Negative | Online Inquiry |
PITPNA Gene Knockout Cell Lines are specialized cellular models engineered to specifically disrupt the function of the Phosphatidylinositol Transfer Protein Alpha (PITPNA) gene. These cell lines are invaluable tools for researchers investigating the diverse biological roles of PITPNA, including its critical involvement in phosphoinositide signaling pathways. By employing gene editing techniques such as CRISPR-Cas9, these cell lines facilitate the study of gene function and the resultant phenotypic changes, providing insights into cellular processes such as lipid metabolism, signal transduction, and membrane dynamics.
The key function of these knockout cell lines lies in their ability to mimic various pathological states by eliminating the expression of the PITPNA gene. This loss-of-function model allows researchers to dissect the mechanistic roles of PITPNA in vivo and in vitro, and to explore its implications in diseases such as cancer, neurodegeneration, and metabolic disorders. The precise control of gene expression offered by these knockout models presents an opportunity for elucidating the intricacies of cellular pathways and developing targeted therapeutic strategies.
From a scientific perspective, PITPNA Gene Knockout Cell Lines serve as a significant advancement over traditional methods, providing a homogeneous population of cells devoid of the target gene. This reduces variability and enhances the reproducibility of results, making studies more reliable. Additionally, these cell lines can be utilized in diverse applications, including drug discovery, toxicity testing, and the development of gene therapies.
The use of PITPNA Gene Knockout Cell Lines offers distinct advantages over alternative methods. Their specificity, efficiency, and ease of use set them apart, making them attractive options for researchers looking to accelerate their investigations. By integrating these cell lines into experimental workflows, researchers can unlock new avenues of discovery and achieve profound insights into the mechanisms underlying health and disease.
At [Your Company Name], we pride ourselves on our commitment to advancing scientific research. With our expertise in cell line development and genetic engineering, we provide high-quality biological products that empower researchers and clinicians to address critical questions in biology and medicine. Our PITPNA Gene Knockout Cell Lines exemplify this commitment, offering cutting-edge solutions to support your groundbreaking work.
Please note that all services are for research use only. Not intended for any clinical use.
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