Gene: PIP4P1
Official Full Name: phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1provided by HGNC
Gene Summary: TMEM55B catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate (Ungewickell et al., 2005 [PubMed 16365287]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07844 | PIP4P1 Knockout cell line (HeLa) | Human | PIP4P1 | 1:3~1:6 | Negative | Online Inquiry |
KO07845 | PIP4P1 Knockout cell line (HCT 116) | Human | PIP4P1 | 1:2~1:4 | Negative | Online Inquiry |
KO07846 | PIP4P1 Knockout cell line (HEK293) | Human | PIP4P1 | 1:3~1:6 | Negative | Online Inquiry |
KO07847 | PIP4P1 Knockout cell line (A549) | Human | PIP4P1 | 1:3~1:4 | Negative | Online Inquiry |
PIP4P1 Gene Knockout Cell Lines are genetically modified cellular models designed specifically to investigate the role and function of the PIP4P1 gene in various biological processes. This innovative product leverages advanced CRISPR/Cas9 gene-editing technology to create defined genetic disruptions that allow for precise studies of gene function, protein interactions, and cellular pathways. By knocking out the PIP4P1 gene, researchers can effectively analyze the downstream effects on lipid metabolism and phosphoinositide signaling activities, crucial mechanisms in cellular physiology.
The primary function of PIP4P1 is its involvement in phosphatidylinositol phosphorylation, which plays a pivotal role in intracellular signaling pathways. Understanding how disrupting PIP4P1 impacts cell signaling, membrane dynamics, and cellular responses to external stimuli is essential for elucidating its contributions to diseases, including cancer, neurodegenerative disorders, and metabolic syndromes. These knockout cell lines provide a versatile tool for scientists to dissect these complex interactions in both in vitro and in vivo models.
The scientific importance of PIP4P1 Gene Knockout Cell Lines is particularly pronounced in research and clinical applications. They enable researchers to develop a deeper understanding of the pathological roles of PIP4P1 alterations and guide the development of targeted therapies. Additionally, these models can facilitate drug screening by identifying novel therapeutic compounds that modulate the activity of this gene.
Compared to traditional cell line models, the PIP4P1 Gene Knockout Cell Lines present specific advantages by offering a clean genetic background free from confounding factors, allowing for clearer data interpretation and reproducibility. Researchers can trust that the phenotypic outcomes are a direct result of the knockout event rather than additional genetic variability.
For researchers and clinicians alike, investing in PIP4P1 Gene Knockout Cell Lines represents an invaluable resource that can drive forward understanding in cellular biology and therapeutic development. The superior specificity and application versatility make these cell lines ideal for tackling complex biochemical pathways.
Our company specializes in providing high-quality biological products that support cutting-edge research and clinical applications. With a commitment to innovation and scientific advancement, we ensure that our offerings meet the rigorous demands of modern biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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