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PHLDB3 Knockout Cell Lines

Gene: PHLDB3

Official Full Name: pleckstrin homology like domain family B member 3provided by HGNC

Gene Summary: Enables enzyme binding activity. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15175 PHLDB3 Knockout cell line (HeLa) Human PHLDB3 1:3~1:6 Negative Online Inquiry
KO15176 PHLDB3 Knockout cell line (HCT 116) Human PHLDB3 1:2~1:4 Negative Online Inquiry
KO15177 PHLDB3 Knockout cell line (HEK293) Human PHLDB3 1:3~1:6 Negative Online Inquiry
KO15178 PHLDB3 Knockout cell line (A549) Human PHLDB3 1:3~1:4 Negative Online Inquiry

Background

PHLDB3 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the PH domain and Leucine-rich repeat protein 3 (PHLDB3). These cell lines are the result of precise gene editing techniques, such as CRISPR-Cas9, which specifically disrupt the PHLDB3 gene, allowing researchers to investigate the biological functions, pathways, and regulatory mechanisms associated with this gene’s expression and its role in various cellular processes.

The key function of PHLDB3 gene knockout cell lines lies in their ability to mimic a loss-of-function phenotype, making them essential tools for studying gene function in a controlled environment. By analyzing these knockout lines, researchers can delve into how the absence of PHLDB3 affects cellular processes like signal transduction, cell proliferation, apoptosis, and metabolic regulation. This insight is critical, especially in the context of diseases where PHLDB3 has been implicated, such as certain cancers and metabolic disorders.

The scientific importance of PHLDB3 knockout cell lines is underscored by their potential applications across various research and clinical settings. They serve as pivotal platforms for drug discovery, biomarker identification, and the elucidation of molecular mechanisms involved in pathophysiological conditions. The precise modulation of gene activity through knockout models enhances the reliability of experimental outcomes, thereby contributing to the advancement of personalized medicine approaches.

One of the unique selling points of our PHLDB3 gene knockout cell lines is their high specificity and efficiency compared to conventional genetic manipulation techniques. The use of CRISPR technology provides a precise alteration without the introduction of off-target effects, resulting in more reliable data. These knockout lines are also available with comprehensive characterization and validation data, which ensures researchers can confidently utilize them in their experiments.

By investing in PHLDB3 Gene Knockout Cell Lines, researchers and clinicians gain access to a cutting-edge tool that enhances their understanding of gene function and its implications in health and disease. Our commitment to quality and innovation is reflected in our deep expertise in genetic engineering and cell line development, making us a trusted partner in advancing biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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