Gene: PHC3
Official Full Name: polyhomeotic homolog 3provided by HGNC
Gene Summary: Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Located in nucleoplasm. Part of PRC1 complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15195 | PHC3 Knockout cell line (HeLa) | Human | PHC3 | 1:3~1:6 | Negative | Online Inquiry |
KO15196 | PHC3 Knockout cell line (HCT 116) | Human | PHC3 | 1:2~1:4 | Negative | Online Inquiry |
KO15197 | PHC3 Knockout cell line (HEK293) | Human | PHC3 | 1:3~1:6 | Negative | Online Inquiry |
KO15198 | PHC3 Knockout cell line (A549) | Human | PHC3 | 1:3~1:4 | Negative | Online Inquiry |
PHC3 Gene Knockout Cell Lines are highly specialized biological products designed for advanced genetic research, enabling the precise investigation of the PHC3 gene's functions and its implications in various cellular processes. These cell lines are engineered using CRISPR-Cas9 gene-editing technology, which facilitates the targeted disruption of the PHC3 gene, resulting in a knockout model. This method not only ensures the robustness and specificity of the genetic modification but also minimizes off-target effects that could confound research outcomes.
The key functionality of PHC3 Gene Knockout Cell Lines lies in their ability to elucidate the role of the PHC3 gene in critical biological pathways. Researchers can study cellular responses, protein interactions, and pathway activations that are influenced by the absence of PHC3. This is particularly important in areas such as cancer research, neurobiology, and developmental biology, where gene function can drastically affect disease progression and organismal development.
The scientific importance of these knockout cell lines is underscored by their applications in both basic and translational research. They serve as invaluable tools for validating potential therapeutic targets, screening drug candidates, and understanding disease mechanisms at a molecular level. In clinical settings, the insights gained from these models may inform personalized medicine approaches and lead to more effective treatment strategies.
Compared to alternative models, PHC3 Gene Knockout Cell Lines offer significant advantages, including a high rate of gene disruption efficiency, reproducibility across experimental conditions, and user-friendly protocols. Moreover, because these lines allow for the study of gene function in a controlled environment, they provide a more reliable foundation for drawing conclusions about gene behavior and interaction in vivo.
For researchers and clinicians alike, the PHC3 Gene Knockout Cell Lines represent a critical asset in the quest to uncover the underlying mechanisms of health and disease. With our company's commitment to high-quality biological products and extensive experience in genetic engineering, we ensure that each cell line is validated for consistency and reliability, empowering users to achieve groundbreaking discoveries in their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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