Gene: PFN2
Official Full Name: profilin 2provided by HGNC
Gene Summary: The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08712 | PFN2 Knockout cell line (HeLa) | Human | PFN2 | 1:3~1:6 | Negative | Online Inquiry |
KO08713 | PFN2 Knockout cell line (HCT 116) | Human | PFN2 | 1:2~1:4 | Negative | Online Inquiry |
KO08714 | PFN2 Knockout cell line (HEK293) | Human | PFN2 | 1:3~1:6 | Negative | Online Inquiry |
KO08715 | PFN2 Knockout cell line (A549) | Human | PFN2 | 1:3~1:4 | Negative | Online Inquiry |
PFN2 Gene Knockout Cell Lines are genetically engineered cell lines that have had the Profilin 2 (PFN2) gene inactivated or “knocked out.” This product serves as a vital tool for researchers investigating the cellular and molecular underpinnings of various physiological and pathological processes, particularly those related to the cytoskeleton, cell motility, and signaling pathways. PFN2 is known to play essential roles in actin polymerization and cellular morphology, making these knockout cell lines invaluable for delineating the gene's specific functions in diverse biological contexts.
The key function of PFN2 Gene Knockout Cell Lines lies in their ability to clarify the biological consequences of PFN2 absence, enabling researchers to explore compensatory mechanisms activated by cells in response to the loss of this gene. By examining these altered cell lines, scientists can better understand the implications of PFN2 in conditions such as cancer metastasis, neurological disorders, and immune responses. Moreover, the unique mechanism behind these knockout models allows for in-depth studies of signaling pathways and cytoskeletal dynamics, leading to potentially groundbreaking discoveries in cell biology.
In research and clinical settings, these cell lines stand out for their specificity. Unlike traditional knockouts that may result in off-target effects or compensatory upregulation of related proteins, our PFN2 Gene Knockout Cell Lines offer a clean and precise absence of the PFN2 gene, thus minimizing noise in experimental outcomes. This precision ensures consistent reproducibility, a crucial factor for high-stakes studies and drug development processes.
The advantages of utilizing PFN2 Gene Knockout Cell Lines extend to their ease of use and compatibility with various assays, such as proliferation, migration, and differentiation studies. For researchers delving into the intricacies of gene function, these cell lines provide a powerful tool that aids in uncovering novel therapeutic targets or understanding disease mechanisms.
Our company, with decades of experience in developing high-quality biological reagents, is committed to advancing research with cutting-edge products like PFN2 Gene Knockout Cell Lines. By choosing our products, users can trust they are working with rigorously validated tools that support scientific innovation and facilitate breakthroughs in their fields.
Please note that all services are for research use only. Not intended for any clinical use.
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