Gene: PCGF3
Official Full Name: polycomb group ring finger 3provided by HGNC
Gene Summary: The protein encoded by this gene contains a C3HC4 type RING finger, which is a motif known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31968 | PCGF3 Knockout cell line (HeLa) | Human | PCGF3 | 1:3~1:6 | Negative | Online Inquiry |
KO31969 | PCGF3 Knockout cell line (HCT 116) | Human | PCGF3 | 1:2~1:4 | Negative | Online Inquiry |
KO31970 | PCGF3 Knockout cell line (HEK293) | Human | PCGF3 | 1:3~1:6 | Negative | Online Inquiry |
KO31971 | PCGF3 Knockout cell line (A549) | Human | PCGF3 | 1:3~1:4 | Negative | Online Inquiry |
PCGF3 Gene Knockout Cell Lines are a pioneering biological tool designed to facilitate the study of gene function and regulation in mammalian systems. These cell lines are generated through the precision editing of the PCGF3 gene using CRISPR/Cas9 technology, allowing researchers to create a loss-of-function model that can elucidate the role of this gene in various cellular processes. The crucial mechanism lies in the complete ablation of PCGF3 expression, enabling comprehensive analysis of phenotypic changes that result from the absence of this gene.
The key function of the PCGF3 Gene Knockout Cell Lines lies in their ability to serve as a framework for studying gene interactions, cellular signaling pathways, and the downstream effects on gene expression dynamics. This is especially important in the context of cancer research, developmental biology, and the understanding of genetic diseases, where PCGF3 has been implicated in crucial regulatory networks.
In the realm of scientific research and clinical applications, these cell lines are vital for characterizing potential therapeutic targets and validating the efficacy of new treatment modalities. By utilizing these knockout cells, researchers can perform high-throughput screening and functional assays to identify drug candidates that may restore normal function associated with PCGF3 loss.
A distinct advantage of PCGF3 Gene Knockout Cell Lines is their specificity and reliability. Unlike alternative methods such as RNA interference, which may yield transient and incomplete gene silencing, knockout models provide a definitive approach, producing stable and reproducible phenotypic outcomes. This permanence ensures that findings are robust and can be reliably replicated across different experimental setups.
For researchers and clinicians, PCGF3 Gene Knockout Cell Lines represent an invaluable resource that accelerates discovery and enhances the understanding of gene function in health and disease. With our unwavering commitment to scientific innovation and high-quality biological products, our expertise ensures that these cell lines meet the exceptional standards necessary for groundbreaking research, ultimately driving advancements in the field of molecular biology and genetics.
Please note that all services are for research use only. Not intended for any clinical use.
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