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PCGF1 Knockout Cell Lines

Gene: PCGF1

Official Full Name: polycomb group ring finger 1provided by HGNC

Gene Summary: PCGF1 is a mammalian homolog of the Drosophila polycomb group genes, which act as transcriptional repressors to regulate anterior-posterior patterning in early embryonic development (Nunes et al., 2001 [PubMed 11287196]). See also PCGF2 (MIM 600346).[supplied by OMIM, Aug 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24651 PCGF1 Knockout cell line (HeLa) Human PCGF1 1:3~1:6 Negative Online Inquiry
KO24652 PCGF1 Knockout cell line (HCT 116) Human PCGF1 1:2~1:4 Negative Online Inquiry
KO24653 PCGF1 Knockout cell line (HEK293) Human PCGF1 1:3~1:6 Negative Online Inquiry
KO24654 PCGF1 Knockout cell line (A549) Human PCGF1 1:3~1:4 Negative Online Inquiry

Background

PCGF1 Gene Knockout Cell Lines are specialized cellular systems engineered to silence the PCGF1 gene, which plays a critical role in cellular processes such as gene expression regulation and chromatin modification. By utilizing advanced CRISPR/Cas9 gene editing technology, these cell lines provide researchers with a powerful tool to investigate the precise functions of the PCGF1 gene in various biological contexts.

The primary function of these knockout cell lines is to facilitate the exploration of PCGF1's role in key cellular pathways involving proliferation, differentiation, and epigenetic regulation. The absence of the PCGF1 gene allows scientists to observe the resultant phenotypic changes and alterations in downstream signaling pathways, leading to a deeper understanding of its biological significance. This capability is crucial for elucidating mechanisms underlying diseases such as cancer, where PCGF1's regulatory functions may be disrupted.

In research and clinical applications, PCGF1 Gene Knockout Cell Lines stand out for their capacity to serve as models for studying gene function and for drug development validation. Their well-characterized background ensures reproducibility and reliability in experiments, making them invaluable for basic research as well as translational studies aiming to develop therapeutics targeting the pathways involved.

One of the unique selling points of our PCGF1 Gene Knockout Cell Lines is their precision and the robustness of the gene editing approach employed. Unlike conventional knockdown methods, such as RNA interference, which may result in off-target effects and incomplete gene silencing, our knockout lines offer a complete and stable genetic alteration, allowing for more accurate functional assessments and higher confidence in experimental outcomes.

For researchers and clinicians, these cell lines represent an essential resource for advancing their work in genetics, cell biology, and therapeutic development. By choosing our PCGF1 Gene Knockout Cell Lines, users can enhance their studies with a tool that not only delivers reliable data but also opens new avenues for understanding complex biological processes.

Our company is dedicated to providing high-quality biological products and innovative solutions for the scientific community. With a focus on precision and excellence, we continue to support groundbreaking research through our commitment to delivering advanced cellular models that meet the evolving needs of researchers.

Please note that all services are for research use only. Not intended for any clinical use.

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