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PALLD Knockout Cell Lines

Gene: PALLD

Official Full Name: palladin, cytoskeletal associated proteinprovided by HGNC

Gene Summary: This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06067 PALLD Knockout cell line (HeLa) Human PALLD 1:3~1:6 Negative Online Inquiry
KO06068 PALLD Knockout cell line (HCT 116) Human PALLD 1:2~1:4 Negative Online Inquiry
KO06069 PALLD Knockout cell line (HEK293) Human PALLD 1:3~1:6 Negative Online Inquiry
KO06070 PALLD Knockout cell line (A549) Human PALLD 1:3~1:4 Negative Online Inquiry

Background

PALLD Gene Knockout Cell Lines are a specific type of genetically engineered cell line in which the PALLD gene, known for its role in cytoskeletal dynamics and cell motility, has been inactivated or "knocked out." This innovative product enables researchers to investigate the biological and pathological roles of the PALLD gene with precision. By using CRISPR-Cas9 technology, these cell lines exhibit a complete gene ablation, allowing for the thorough study of gene function, including its involvement in cancer progression, cell migration, and other cellular processes.

The primary mechanism by which PALLD Gene Knockout Cell Lines contribute to research lies in their ability to serve as stable, replicable models for the exploration of gene-related pathways. The absence of the PALLD gene leads to observable alterations in cellular morphology, adhesion properties, and migratory behavior, providing insight into its contribution to various cellular functions. This model opens avenues for developing targeted therapies and understanding disease mechanisms at a cellular level in both in vitro and in vivo studies.

In terms of scientific importance, these cell lines are particularly valuable in cancer research, where elucidating the role of cytoskeletal elements can lead to breakthroughs in treatment strategies. They also have potential applications in studying developmental biology and tissue engineering, representing a versatile tool in modern health science research.

Compared to alternative gene knockout systems, PALLD Gene Knockout Cell Lines offer higher specificity and efficiency, minimizing off-target effects while maximizing the fidelity of gene editing. This precision ensures that researchers can draw robust conclusions about gene function and its implications in health and disease. Furthermore, these cell lines are provided with comprehensive support from our team of experts, ensuring a seamless integration into your research protocols.

Overall, PALLD Gene Knockout Cell Lines represent an essential addition to any laboratory focused on gene function studies, offering a unique opportunity to enhance understanding of complex biological processes. With our company’s long-standing expertise in advanced genetic engineering and cell line development, we are dedicated to providing researchers with top-tier, reliable tools that propel their scientific discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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