Gene: P2RX5
Official Full Name: purinergic receptor P2X 5provided by HGNC
Gene Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3). [provided by RefSeq, Mar 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08091 | P2RX5 Knockout cell line (HeLa) | Human | P2RX5 | 1:3~1:6 | Negative | Online Inquiry |
KO08092 | P2RX5 Knockout cell line (HCT 116) | Human | P2RX5 | 1:2~1:4 | Negative | Online Inquiry |
KO08093 | P2RX5 Knockout cell line (HEK293) | Human | P2RX5 | 1:3~1:6 | Negative | Online Inquiry |
KO08094 | P2RX5 Knockout cell line (A549) | Human | P2RX5 | 1:3~1:4 | Negative | Online Inquiry |
P2RX5 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to knock out the P2RX5 gene, which encodes purinergic receptors critical for numerous cellular processes, including inflammation and immune response. These cells enable researchers to explore the role of P2RX5 in various biological contexts, particularly its contributions to cell signaling pathways and interactions with extracellular ATP, a key regulator of cellular communication and physiological responses.
The key function of these knockout cell lines lies in their ability to eliminate the expression of the P2RX5 receptor, allowing scientists to study the resulting phenotypic changes and associated cellular mechanisms without the confounding effects of this receptor. By utilizing P2RX5 knockout models, researchers can investigate the gene's role in pain pathways, neurogenic inflammation, and potential implications in diseases such as chronic pain syndromes and autoimmune disorders. The knockout approach facilitates a clearer understanding of receptor-specific signaling and offers insights into therapeutic targets.
The scientific importance of P2RX5 Gene Knockout Cell Lines extends into both basic and applied research fields, particularly in pharmacology and toxicology. In clinical settings, these models can provide valuable data for drug discovery and development by elucidating the effects of pharmacological agents on cells lacking P2RX5 signaling.
One of the primary advantages of these knockout cell lines is their precision and reliability in studying the specific contributions of P2RX5, as compared to alternative methods like pharmacological inhibition, which may exert off-target effects. Additionally, using knockout models provides a more straightforward interpretation of experimental outcomes, which can be critical for validating hypotheses in complex biological systems.
For researchers and clinicians, the value of P2RX5 Gene Knockout Cell Lines is highlighted by their potential to unlock novel therapeutic strategies and enhance understanding of critical biological processes. By using validated cell lines, scientists can achieve more robust and reproducible results, ultimately leading to advancements in healthcare and therapeutic interventions.
Our company specializes in providing high-quality biological products, harnessing cutting-edge genetic engineering techniques to enable groundbreaking research. We ensure rigorous quality controls in our offerings, supporting the scientific community's pursuit of knowledge and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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