Gene: OR5G3
Official Full Name: olfactory receptor family 5 subfamily G member 3 (gene/pseudogene)provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25826 | OR5G3 Knockout cell line (HeLa) | Human | OR5G3 | 1:3~1:6 | Negative | Online Inquiry |
KO25827 | OR5G3 Knockout cell line (HCT 116) | Human | OR5G3 | 1:2~1:4 | Negative | Online Inquiry |
KO25828 | OR5G3 Knockout cell line (HEK293) | Human | OR5G3 | 1:3~1:6 | Negative | Online Inquiry |
KO25829 | OR5G3 Knockout cell line (A549) | Human | OR5G3 | 1:3~1:4 | Negative | Online Inquiry |
OR5G3 Gene Knockout Cell Lines represent a significant advancement in cellular biology research by enabling the study of the olfactory receptor OR5G3 in a controlled environment. These specialized cell lines are engineered to have disruptions in the OR5G3 gene, effectively eliminating its expression. This gene plays a vital role in olfaction and has implications in the understanding of sensory processing and related disorders.
The primary function of the OR5G3 Gene Knockout Cell Lines includes providing a robust platform for investigating the biological roles and signaling pathways associated with the OR5G3 receptor. Researchers can conduct a variety of assays to evaluate the consequences of gene knockout on olfactory signaling, receptor interactions, and the cellular response to various ligands. This is crucial for understanding not only olfactory mechanisms but also broader aspects of G protein-coupled receptor biology.
Scientifically, the availability of these knockout cell lines is invaluable for drug discovery and development. These cell lines can be employed in high-throughput screening assays to identify novel compounds that selectively target or modulate the OR5G3 receptor, facilitating potential therapeutic discovery for olfactory dysfunction and related conditions. Their application extends to neurobiology, pharmacology, and cell signaling studies, making them an essential resource for both academic and clinical research.
OR5G3 Gene Knockout Cell Lines offer several advantages over alternative methods, such as transient gene silencing or CRISPR-modified alternatives that may not yield stable, long-term results. The consistency and reliability of these knockout cell lines in experiments allow researchers to draw more accurate conclusions. Additionally, they provide a quicker and more efficient means of generating experimental data, which is particularly advantageous for time-sensitive research projects.
For researchers and clinicians looking to explore or manipulate the nuances of olfactory receptor signaling, OR5G3 Gene Knockout Cell Lines are an indispensable asset. Their precision and stability increase the potential for groundbreaking discoveries in sensory biology. Our company boasts extensive expertise in genetic engineering and offers a comprehensive selection of specialized cell lines designed to aid the scientific community, ensuring that advanced research can continue to thrive.
Please note that all services are for research use only. Not intended for any clinical use.
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