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OR5AC1 Knockout Cell Lines

Gene: OR5AC1

Official Full Name: olfactory receptor family 5 subfamily AC member 1 (gene/pseudogene)provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25807 OR5AC1 Knockout cell line (HeLa) Human OR5AC1 1:3~1:6 Negative Online Inquiry
KO25808 OR5AC1 Knockout cell line (HCT 116) Human OR5AC1 1:2~1:4 Negative Online Inquiry
KO25809 OR5AC1 Knockout cell line (HEK293) Human OR5AC1 1:3~1:6 Negative Online Inquiry
KO25810 OR5AC1 Knockout cell line (A549) Human OR5AC1 1:3~1:4 Negative Online Inquiry

Background

OR5AC1 Gene Knockout Cell Lines represent a powerful tool for biological and biomedical research, specifically designed to study the olfactory receptor family. These genetically modified cell lines facilitate the investigation of OR5AC1, a member of the olfactory receptor gene family implicated in scent detection and neurosensory signaling. By utilizing CRISPR/Cas9 technology, these knockout cell lines enable researchers to investigate the functional significance of the OR5AC1 gene, exploring its role in olfactory signaling pathways and potential alterations in disease states.

The key function of the OR5AC1 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for the examination of gene expression, receptor activity, and cellular behaviors in the absence of the OR5AC1 gene. This allows researchers to dissect the downstream signaling pathways that are affected by its knockout, ultimately enhancing our understanding of how olfactory receptors contribute to sensory processing and behavioral responses.

From a scientific perspective, these cell lines hold significant importance in pharmacology and toxicology, offering insights into how olfactory receptors influence drug metabolism and toxicity. They also serve as invaluable platforms in the study of neurodegenerative diseases and other disorders linked to sensory deficits. Compared to alternative systems, including traditional knockdown strategies, our gene knockout cell lines guarantee a complete absence of the target gene, minimizing the risk of off-target effects and enhancing the precision of experimental outcomes.

For researchers and clinicians, OR5AC1 Gene Knockout Cell Lines provide a unique opportunity to delve deeper into olfactory biology, with implications that extend to broader areas such as neurobiology, environmental sensing, and therapeutic development. The ability to manipulate gene expression with high specificity opens new avenues for understanding the molecular basis of olfactory-related phenomena and disorders.

Our company prides itself on being at the forefront of genetic engineering and cell line development, leveraging cutting-edge technologies to deliver reliable, scalable solutions tailored to the evolving needs of the scientific community. Our commitment to quality and innovation ensures that our products, like the OR5AC1 Gene Knockout Cell Lines, empower researchers to achieve groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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