Gene: OR52E1
Official Full Name: olfactory receptor family 52 subfamily E member 1 (gene/pseudogene)provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15439 | OR52E1 Knockout cell line (HeLa) | Human | OR52E1 | 1:3~1:6 | Negative | Online Inquiry |
KO15440 | OR52E1 Knockout cell line (HCT 116) | Human | OR52E1 | 1:2~1:4 | Negative | Online Inquiry |
KO15441 | OR52E1 Knockout cell line (HEK293) | Human | OR52E1 | 1:3~1:6 | Negative | Online Inquiry |
KO15442 | OR52E1 Knockout cell line (A549) | Human | OR52E1 | 1:3~1:4 | Negative | Online Inquiry |
OR52E1 Gene Knockout Cell Lines are a cutting-edge biological tool designed to study the functional role of the OR52E1 gene, a member of the olfactory receptor family implicated in various physiological processes. These specially developed cell lines feature a targeted knockout of the OR52E1 gene, allowing researchers to investigate gene function, signaling pathways, and the downstream effects of OR52E1 depletion. The ability to precisely edit the genome using CRISPR-Cas9 technology has ensured that these knockout cell lines exhibit specific and reproducible genetic modifications.
The primary function of the OR52E1 Gene Knockout Cell Lines is to serve as a robust model for studying olfactory transduction mechanisms and their influence on nervous system activities. By eliminating the OR52E1 gene, researchers can elucidate the receptor's role in various sensory and neurological pathways, providing insights that are critical for advancing our understanding of conditions related to olfactory dysfunction and neurobiology.
In both research and clinical contexts, these cell lines offer a versatile system for drug discovery, target validation, and therapeutic development. Their application is especially relevant for the pharmaceutical industry and academia, where understanding the role of GPCRs in disease mechanisms can lead to innovative treatment options.
What sets OR52E1 Gene Knockout Cell Lines apart from other models is their high specificity and reliability, combined with the ease of use typical of established cell culture systems. Researchers benefit from consistent results due to the well-characterized background of the cell lines, which minimizes biological variability that could confound experimental outcomes.
In summary, the OR52E1 Gene Knockout Cell Lines represent a powerful resource for researchers seeking to explore the nuances of olfactory receptor biology and its implications in various health contexts. With a commitment to excellence in biological product development, our company ensures that these cell lines are of the highest quality, underpinned by extensive scientific expertise and a dedication to advancing research capabilities.
Please note that all services are for research use only. Not intended for any clinical use.
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