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OR51H1 Knockout Cell Lines

Gene: OR51H1

Official Full Name: olfactory receptor family 51 subfamily H member 1provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21337 OR51H1 Knockout cell line (HeLa) Human OR51H1 1:3~1:6 Negative Online Inquiry
KO21338 OR51H1 Knockout cell line (HCT 116) Human OR51H1 1:2~1:4 Negative Online Inquiry
KO21339 OR51H1 Knockout cell line (HEK293) Human OR51H1 1:3~1:6 Negative Online Inquiry
KO21340 OR51H1 Knockout cell line (A549) Human OR51H1 1:3~1:4 Negative Online Inquiry

Background

OR51H1 Gene Knockout Cell Lines represent a significant advancement in biological research, specifically tailored for studying the function and implications of the OR51H1 gene, which is known to play a role in olfactory signaling and potential relevance in various diseases. These cell lines are engineered through CRISPR-Cas9 technology to effectively disable the OR51H1 gene, allowing researchers to investigate the biological consequences of its absence in controlled environments.

The primary function of the OR51H1 Gene Knockout Cell Lines is to facilitate in-depth studies into olfactory receptor signaling pathways and their broader implications in neurological and pathological conditions. By observing changes in cellular behavior, gene expression profiles, and metabolic processes following knockout, researchers can unravel the complexities of sensory perception and its interconnection with disease mechanisms, such as certain cancer types and neurodegenerative disorders.

The scientific importance of these cell lines extends to both research and clinical applications. They offer a powerful tool for drug discovery and biomarker identification, particularly in understanding how variations in olfactory receptor gene expression may influence individual responses to therapies. This product enhances the ability to develop novel treatment strategies and to predict patient outcomes based on genetic backgrounds.

Compared to traditional models, the OR51H1 Gene Knockout Cell Lines offer unparalleled specificity and a high degree of reproducibility. By using advanced genome-editing techniques, these cell lines eliminate the off-target effects commonly associated with older gene manipulation methods, thereby increasing the reliability of experimental data.

For researchers and clinicians, these cell lines provide a unique opportunity to unlock new insights into the role of olfactory receptors in health and disease. By utilizing OR51H1 knockout models, they not only gain a deeper understanding of the underlying biological processes but also pave the way for innovative therapeutic advancements.

Our commitment to pioneering genetic research is reflected in our development of these OR51H1 Gene Knockout Cell Lines. With a focus on precision and scientific rigor, our company stands at the forefront of providing high-quality biological products that empower researchers and clinicians to advance their work in genetics and molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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