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OR4Q2 Knockout Cell Lines

Gene: OR4Q2

Official Full Name: olfactory receptor family 4 subfamily Q member 2 (gene/pseudogene)provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15488 OR4Q2 Knockout cell line (HeLa) Human OR4Q2 1:3~1:6 Negative Online Inquiry
KO15489 OR4Q2 Knockout cell line (HCT 116) Human OR4Q2 1:2~1:4 Negative Online Inquiry
KO15490 OR4Q2 Knockout cell line (HEK293) Human OR4Q2 1:3~1:6 Negative Online Inquiry
KO15491 OR4Q2 Knockout cell line (A549) Human OR4Q2 1:3~1:4 Negative Online Inquiry

Background

OR4Q2 Gene Knockout Cell Lines are specialized cellular models engineered to silence the expression of the OR4Q2 gene, an olfactory receptor implicated in various physiological processes and potential disease mechanisms. These cell lines serve as indispensable tools for the study of gene function, signal transduction pathways, and the exploration of receptor-ligand interactions in a controlled setting. The gene knockout mechanism is typically achieved through advanced genome-editing technologies, such as CRISPR-Cas9, which induce targeted double-strand breaks, followed by the error-prone repair pathways that result in frameshift mutations effectively eliminating gene function.

The primary function of these cell lines is to facilitate the investigation of OR4Q2-related signaling pathways and their impact on cellular behavior. By utilizing these knockout lines, researchers can elucidate the biological role of the OR4Q2 gene in various contexts, such as neuronal signaling and potential associations with sensory perception. This has profound implications for both fundamental research and clinical applications, as understanding the role of olfactory receptors may lead to breakthroughs in treating olfactory dysfunction, neurodegenerative diseases, and even cancer.

One unique selling point of OR4Q2 Gene Knockout Cell Lines is their specificity and precision. Unlike traditional methods that can result in off-target effects, these engineered lines provide a reliable approach to studying the role of the OR4Q2 gene in isolation. Moreover, they have been validated for consistency and reproducibility, ensuring that users can achieve dependable results in their experiments.

For researchers and clinicians, these cell lines provide a valuable resource that enhances experimental robustness and accelerates discovery. By integrating OR4Q2 knockout lines into studies, users can generate significant insights into gene function, paving the way for new therapeutic approaches and advancements in understanding associated diseases.

We at [Your Company], a leader in the field of genetic engineering and the production of specialized biological reagents, pride ourselves on delivering high-quality, well-characterized models such as the OR4Q2 Gene Knockout Cell Lines. This product exemplifies our commitment to advancing research capabilities and our dedication to supporting the scientific community with innovative solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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