Gene: OR1P1
Official Full Name: olfactory receptor family 1 subfamily P member 1 (gene/pseudogene)provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34211 | OR1P1 Knockout cell line (HeLa) | Human | OR1P1 | 1:3~1:6 | Negative | Online Inquiry |
KO34212 | OR1P1 Knockout cell line (HCT 116) | Human | OR1P1 | 1:2~1:4 | Negative | Online Inquiry |
KO34213 | OR1P1 Knockout cell line (HEK293) | Human | OR1P1 | 1:3~1:6 | Negative | Online Inquiry |
KO34214 | OR1P1 Knockout cell line (A549) | Human | OR1P1 | 1:3~1:4 | Negative | Online Inquiry |
OR1P1 Gene Knockout Cell Lines are intricately engineered cellular models designed to facilitate the study of the OR1P1 gene, known for its role in olfactory signal transduction and potential involvement in various physiological processes. These cell lines are generated through cutting-edge CRISPR-Cas9 gene-editing technology, ensuring precise removal of the OR1P1 gene, which makes them invaluable for dissecting the functional implications of OR1P1 deletion in cellular contexts.
The key function of OR1P1 Gene Knockout Cell Lines lies in their ability to allow researchers to explore the ramifications of OR1P1 loss on cellular behavior, including receptor activation pathways, signal transduction, and downstream gene expression changes. By comparing these knockout cells with wild-type counterparts, scientists can elucidate the gene's contributions to olfaction and its roles in health and disease. This capability is critical for understanding how dysregulation of olfactory pathways may affect conditions like anosmia or other neurodegenerative diseases.
In terms of scientific importance, these cell lines serve as a robust model for translational research. They provide a platform for drug discovery and toxicological studies where the interplay between olfactory receptors and potential therapeutic compounds can be scrutinized. By offering insights into the molecular mechanisms of OR1P1, these cell lines pave the way for innovative interventions targeting related pathways.
One of the standout advantages of OR1P1 Gene Knockout Cell Lines is their specificity and reproducibility, key factors often lacking in conventional models. Compared to other models, these knockout lines provide a direct approach to gene function analysis, eliminating off-target effects and thereby enhancing the reliability of experimental outcomes.
For researchers and clinicians focused on developmental biology, neurobiology, or pharmacology, the value of the OR1P1 Gene Knockout Cell Lines is immense. They open avenues for hypothesis-driven studies and foster a deeper understanding of gene function in complex biological systems.
Our company prides itself on its expertise in developing state-of-the-art biological products, including customized cell lines, designed to accelerate scientific discovery and enhance research capabilities. Our commitment to quality and innovation ensures that our products meet the highest standards, empowering researchers to achieve significant breakthroughs in their fields.
Please note that all services are for research use only. Not intended for any clinical use.
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