Gene: OR1E3
Official Full Name: olfactory receptor family 1 subfamily E member 3 (gene/pseudogene)provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34215 | OR1E3 Knockout cell line (HeLa) | Human | OR1E3 | 1:3~1:6 | Negative | Online Inquiry |
KO34216 | OR1E3 Knockout cell line (HCT 116) | Human | OR1E3 | 1:2~1:4 | Negative | Online Inquiry |
KO34217 | OR1E3 Knockout cell line (HEK293) | Human | OR1E3 | 1:3~1:6 | Negative | Online Inquiry |
KO34218 | OR1E3 Knockout cell line (A549) | Human | OR1E3 | 1:3~1:4 | Negative | Online Inquiry |
OR1E3 Gene Knockout Cell Lines are advanced laboratory tools designed for the investigation and functional analysis of the OR1E3 gene, which is known to play a crucial role in various cellular processes, particularly in olfactory signaling pathways. These cell lines have been genetically modified to absence of the OR1E3 gene, thereby enabling researchers to study the downstream effects of gene deletion and elucidate its biological role in both physiological and pathological contexts.
The primary function of OR1E3 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for examining the impacts of OR1E3 gene disruption. By utilizing CRISPR/Cas9 technology, the gene's sequences are precisely edited, resulting in a knockout phenotype that allows for the assessment of changes in cellular behavior, signal transduction pathways, and response to external stimuli. These cell lines serve as essential models for research targeting olfactory receptors and their involvement in taste perception, neurobiology, and disease mechanisms.
The scientific importance of these cell lines is underscored by their wide-ranging applications, from basic research to clinical studies. They facilitate the exploration of gene function, drug discovery, and the development of therapeutic strategies for olfactory dysfunctions or related conditions. Moreover, they are indispensable in pharmacological studies that require precise models to evaluate the efficacy and safety of compounds targeting olfactory receptor-mediated pathways.
When compared to alternative models, OR1E3 Gene Knockout Cell Lines offer unique advantages such as high specificity, reproducibility, and ease of use. Unlike traditional knockout methods that may result in off-target effects or variable expression levels, our targeted knockout approach ensures a clean and consistent genetic background. This reliability is crucial for generating valid and reproducible data across experiments, making these cell lines a preferred choice for cutting-edge research applications.
For researchers, clinicians, and biotech companies, OR1E3 Gene Knockout Cell Lines represent a significant asset, delivering a robust tool for gene function analysis, potential biomarker identification, and the development of novel therapeutic interventions. The ability to manipulate gene expression at a precise level facilitates innovative research that can lead to breakthroughs in our understanding of genetic regulation and its implications for health and disease.
Our company prides itself on its dedication to advancing research through the provision of high-quality biological products. With a focus on innovation and excellence, we are committed to supporting the scientific community in their quest to uncover the complexities of genetic and cellular interactions, ultimately aiming to drive forward medical research and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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