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OR10J3 Knockout Cell Lines

Gene: OR10J3

Official Full Name: olfactory receptor family 10 subfamily J member 3 (gene/pseudogene)provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This gene is considered a pseudogene because the encoded protein is truncated and missing the last transmembrane domain in several mammals.[provided by RefSeq, Jun 2021]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25803 OR10J3 Knockout cell line (HeLa) Human OR10J3 1:3~1:6 Negative Online Inquiry
KO25804 OR10J3 Knockout cell line (HCT 116) Human OR10J3 1:2~1:4 Negative Online Inquiry
KO25805 OR10J3 Knockout cell line (HEK293) Human OR10J3 1:3~1:6 Negative Online Inquiry
KO25806 OR10J3 Knockout cell line (A549) Human OR10J3 1:3~1:4 Negative Online Inquiry

Background

OR10J3 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the OR10J3 gene, a member of the olfactory receptor gene family implicated in various physiological processes including metabolic regulation and neuronal signaling. By employing CRISPR-Cas9 technology to generate these knockout lines, researchers can effectively inhibit OR10J3 expression, allowing for the examination of its role in both normal biological processes and pathological conditions.

These cell lines function by providing a controlled environment where the absence of the OR10J3 gene can be precisely analyzed. This enables scientists to observe changes in cellular behavior, signaling pathways, and gene expression profiles, thus elucidating the gene's functional implications. The knockouts serve as critical tools for studying olfactory receptor mechanisms, contributing to our broader understanding of sensory biology and potential therapeutic targets.

Scientifically, OR10J3 Gene Knockout Cell Lines hold immense value in both research and clinical applications. They are instrumental in drug discovery processes, particularly in identifying new pharmacological agents that may interact with olfactory receptors, thereby influencing metabolic diseases, neurological disorders, and even cancer. Their use in basic scientific studies furthers insights into receptor biology and the intricate networks of gene-regulatory pathways.

One of the primary advantages of our OR10J3 knockout lines lies in their specificity and reproducibility. Unlike alternatives that may produce variable results or lack uniformity in gene expression, these cell lines offer consistent performance across experiments, thereby enhancing data reliability. Additionally, the ease of use in various cell culture settings and compatibility with high-throughput screening make them an indispensable asset for laboratories focused on genetic research.

Researchers and clinicians seeking to expand their understanding of olfactory receptor biology will find OR10J3 Gene Knockout Cell Lines to be a valuable resource. Their ability to facilitate targeted investigations provides a unique opportunity to uncover novel findings that could lead to breakthrough developments in therapeutic strategies.

Our company specializes in innovative biological products, and we are proud to offer these cutting-edge knockout cell lines, backed by our extensive expertise in genetic engineering and cell biology. By choosing our OR10J3 Gene Knockout Cell Lines, you are equipping your research with precise, high-quality tools that stand out in the ever-evolving landscape of biological science.

Please note that all services are for research use only. Not intended for any clinical use.

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