Gene: OLIG1
Official Full Name: oligodendrocyte transcription factor 1provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Predicted to be involved in axon development; positive regulation of transcription by RNA polymerase II; and sensory organ development. Predicted to act upstream of or within neuron fate commitment. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02061 | OLIG1 Knockout cell line (HEK293) | Human | OLIG1 | 1:3~1:6 | Negative | Online Inquiry |
OLIG1 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to facilitate the study of the OLIG1 gene, which plays a critical role in oligodendrocyte differentiation and myelination within the central nervous system. These cell lines serve as a powerful tool for researchers aiming to elucidate the biological pathways influenced by OLIG1, enabling in-depth investigations into neurodevelopmental disorders, multiple sclerosis, and other demyelinating diseases.
The primary function of OLIG1 Gene Knockout Cell Lines is to allow for the observation of phenotypic changes that occur when the OLIG1 gene is rendered inoperative. By creating a targeted knockout of OLIG1, researchers can dissect the gene's regulatory effects on cellular processes, such as cell proliferation, survival, and differentiation. The loss-of-function experiments conducted using these cell lines provide insights into the underlying mechanisms of diseases associated with oligodendrocyte dysfunction.
From a scientific perspective, the availability of OLIG1 Gene Knockout Cell Lines is crucial for advancing our understanding of neurological conditions and paving the way for the discovery of therapeutic targets. Their application extends to drug screening, gene therapy research, and the development of novel treatment strategies in clinical settings.
In comparison to traditional cell lines, OLIG1 Gene Knockout Cell Lines offer several advantages, including specificity in genetic manipulation and the elimination of confounding variables associated with background expression of the OLIG1 gene. This tailored approach enhances the reliability and reproducibility of experimental results, making these cell lines an essential asset for any laboratory focused on neurobiology or genetic research.
By leveraging OLIG1 Gene Knockout Cell Lines, researchers can not only drive impactful discoveries but also contribute to a deeper understanding of the complexities of the central nervous system. Our company, renowned for its expertise in developing precise and innovative biological products, is committed to providing unparalleled resources to empower scientists and clinicians alike in their quest for groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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