Gene: ODAD4
Official Full Name: outer dynein arm docking complex subunit 4provided by HGNC
Gene Summary: This gene encodes a tetratricopeptide repeat domain-containing protein that localizes to ciliary axonmenes and plays a role in the docking of the outer dynein arm to cilia. Mutations in this gene cause severely reduced ciliary motility and the disorder CILD35 (ciliary dyskinesia,primary, 35). Primary ciliary dyskinesia is often associated with recurrent respiratory infections, immotile spermatozoa, and situs inversus; an inversion in left-right body symmetry. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15528 | ODAD4 Knockout cell line (HeLa) | Human | ODAD4 | 1:3~1:6 | Negative | Online Inquiry |
KO15529 | ODAD4 Knockout cell line (HEK293) | Human | ODAD4 | 1:3~1:6 | Negative | Online Inquiry |
KO15530 | ODAD4 Knockout cell line (A549) | Human | ODAD4 | 1:3~1:4 | Negative | Online Inquiry |
ODAD4 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to elucidate the functional implications of the ODAD4 gene in various biological contexts. These knockout cell lines are invaluable tools for researchers aiming to dissect gene functions, explore molecular pathways, and assess the role of ODAD4 in health and disease. By employing advanced gene editing technologies such as CRISPR-Cas9, these cell lines have been systematically engineered to lack the expression of the ODAD4 gene, enabling precise study of gene-related phenotypes.
The ODAD4 gene is implicated in numerous cellular processes, including transcriptional regulation, cellular differentiation, and response to environmental stimuli. The absence of ODAD4 in these cell lines allows for in-depth analysis of these processes and helps to unravel the gene's role in pathophysiological conditions, such as cancer and developmental disorders. Researchers can utilize these models to perform vital experiments such as gene expression profiling, pathway analysis, and drug response studies, enhancing our understanding of gene interactions and potential therapeutic targets.
One of the significant advantages of using ODAD4 Gene Knockout Cell Lines over traditional cell models is the specificity and reliability of results derived from a controlled genetic background. This precision aids in generating reproducible data, which is crucial for downstream applications. Furthermore, these cell lines can facilitate high-throughput screening processes that are essential in drug discovery and development.
The value of ODAD4 Gene Knockout Cell Lines extends beyond just academic research; they serve as potential platforms for clinical diagnostics and therapeutic development. By providing insight into the gene's functionality, these models enable the identification of novel biomarkers and therapeutic strategies, making them essential tools in translational medicine.
Our company, with its profound expertise in genetic engineering and cellular models, is dedicated to providing high-quality biological products that empower scientists and clinicians to advance their research and improve patient outcomes. With a commitment to innovation, we continue to support breakthroughs in molecular biology and genetics, ensuring our customers have access to the resources they need for success.
Please note that all services are for research use only. Not intended for any clinical use.
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