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NXPH4 Knockout Cell Lines

Gene: NXPH4

Official Full Name: neurexophilin 4provided by HGNC

Gene Summary: Predicted to enable signaling receptor binding activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Predicted to be active in GABA-ergic synapse. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31027 NXPH4 Knockout cell line (HeLa) Human NXPH4 1:3~1:6 Negative Online Inquiry
KO31028 NXPH4 Knockout cell line (HCT 116) Human NXPH4 1:2~1:4 Negative Online Inquiry
KO31029 NXPH4 Knockout cell line (HEK293) Human NXPH4 1:3~1:6 Negative Online Inquiry
KO31030 NXPH4 Knockout cell line (A549) Human NXPH4 1:3~1:4 Negative Online Inquiry

Background

NXPH4 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to functionally characterize the role of the NXPH4 gene in various biological processes. These cell lines have undergone precise CRISPR-Cas9 mediated knockout technology to effectively disable the NXPH4 gene, allowing researchers to study the resulting phenotypic changes and molecular pathways disrupted by this alteration.

The primary mechanism of action involves the disruption of gene expression associated with NXPH4, a gene implicated in synaptic transmission and neuronal function. By observing the KO cell lines, scientists can elucidate NXPH4's contributions to neurodevelopmental processes, signal transduction, and potential involvement in neurological disorders. This makes NXPH4 knockout models invaluable for investigating the gene’s role in health and disease, refining therapeutic strategies that target synaptic-related dysfunction.

In both research and clinical settings, these cell lines serve as essential tools for drug discovery and disease modeling, contributing crucial information in the understanding of complex genetic interactions and cellular mechanisms. Notably, NXPH4 knockout models exhibit significant advantages over alternative systems, such as wild-type lines or transient knockdown approaches, as they provide stable and reproducible results vital for long-term studies.

Researchers and clinicians can derive immense value from NXPH4 Gene Knockout Cell Lines due to their specificity and reliability, enhancing experimental design and leading to more robust findings. With an unwavering commitment to precision and innovation, our company offers extensive expertise in genetic engineering and cellular biology, positioning us as a trusted partner in advancing scientific research and therapeutic developments.

Please note that all services are for research use only. Not intended for any clinical use.

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