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NXPE3 Knockout Cell Lines

Gene: NXPE3

Official Full Name: neurexophilin and PC-esterase domain family member 3provided by HGNC

Gene Summary: This gene encodes a member of the neurexophilin family of neuropeptide-like glycoproteins. The encoded protein contains a variable N-terminal domain, a highly conserved neurexophilin and PC-esterase (NXPE) central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein binds alpha neurexins, a group of presynaptic transmembrane receptors that promote adhesion between dendrites and axons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23375 NXPE3 Knockout cell line (HeLa) Human NXPE3 1:3~1:6 Negative Online Inquiry
KO23376 NXPE3 Knockout cell line (HCT 116) Human NXPE3 1:2~1:4 Negative Online Inquiry
KO23377 NXPE3 Knockout cell line (HEK293) Human NXPE3 1:3~1:6 Negative Online Inquiry
KO23378 NXPE3 Knockout cell line (A549) Human NXPE3 1:3~1:4 Negative Online Inquiry

Background

NXPE3 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology research, designed to facilitate the in-depth study of the NXPE3 gene, a protein-coding gene associated with various biological processes and diseases. These specifically engineered cell lines have been created using CRISPR-Cas9 genome editing technology, which allows for the precise disruption of the NXPE3 gene, enabling researchers to explore its function and impact on cellular behavior.

The primary function of NXPE3 Gene Knockout Cell Lines is to serve as a model for investigating the biological role of the NXPE3 gene in various cellular contexts, including its involvement in pathways associated with neuronal development and function. By removing the gene's activity, researchers can observe phenotypic changes, assess alterations in signaling pathways, and evaluate the effects on cell proliferation, differentiation, and apoptosis. This makes the NXPE3 knockout model an invaluable resource for dissecting the molecular underpinnings of diseases where NXPE3 is implicated.

From a scientific perspective, these cell lines hold significant importance within both research and clinical settings. They offer a robust platform for drug development, disease modeling, and functional genomics studies. Researchers can leverage these knockout cell lines to assess potential therapeutic targets, analyze cellular responses to novel compounds, and elucidate mechanisms of disease progression or recovery.

What sets NXPE3 Gene Knockout Cell Lines apart from alternative products is their reliable and reproducible knockout efficiency, as well as the comprehensive characterization provided alongside them. Each cell line is validated through rigorous testing, ensuring that users have access to high-quality models. Furthermore, the cell lines are compatible with various assays and can be easily integrated into existing workflows.

For researchers and clinicians alike, the value of NXPE3 Gene Knockout Cell Lines lies in their ability to accelerate discoveries in gene function and therapeutic strategies. By utilizing these specialized models, users can enhance the quality and relevance of their research outcomes.

At our company, we are committed to providing advanced biological tools that empower researchers in their quest for knowledge and innovation. Our expertise in genomic engineering and cell line development assures you of high-performance products tailored to meet the demands of contemporary scientific research.

Please note that all services are for research use only. Not intended for any clinical use.

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