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NTMT2 Knockout Cell Lines

Gene: NTMT2

Official Full Name: N-terminal Xaa-Pro-Lys N-methyltransferase 2provided by HGNC

Gene Summary: Enables N-terminal protein N-methyltransferase activity. Involved in N-terminal protein amino acid methylation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05158 NTMT2 Knockout cell line (HeLa) Human NTMT2 1:3~1:6 Negative Online Inquiry
KO05159 NTMT2 Knockout cell line (HCT 116) Human NTMT2 1:2~1:4 Negative Online Inquiry
KO05160 NTMT2 Knockout cell line (HEK293) Human NTMT2 1:3~1:6 Negative Online Inquiry
KO05161 NTMT2 Knockout cell line (A549) Human NTMT2 1:3~1:4 Negative Online Inquiry

Background

NTMT2 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology research, designed specifically to study the functional implications of gene NTMT2 in various biological contexts. These cell lines are engineered using CRISPR-Cas9 technology, effectively disrupting the NTMT2 gene, which encodes for the N-terminal methyltransferase 2 enzyme. This enzyme plays a crucial role in regulating protein function via N-terminal methylation, impacting cellular signaling pathways and gene expression profiles.

The key function of these knockout cell lines lies in their ability to facilitate the investigation of the NTMT2 gene's contribution to processes such as cell growth, differentiation, and apoptosis. By employing these cell lines, researchers can establish the phenotypic consequences of NTMT2 loss-of-function, shedding light on its relevance in diseases, including cancer, neurodegeneration, and metabolic disorders. The precise gene editing employed ensures that researchers can obtain reproducible results across different experimental conditions, enhancing the validity of their findings.

The scientific importance of NTMT2 Gene Knockout Cell Lines extends to both basic research and therapeutic applications. In clinical settings, understanding the role of NTMT2 might reveal novel biomarkers for disease progression or therapeutic targets, thereby leading to innovative treatment strategies. When compared to other gene knockout models, NTMT2 cell lines offer superior specificity and reduced off-target effects, making them more reliable for functional studies.

For researchers and clinicians, NTMT2 Gene Knockout Cell Lines are invaluable assets, providing insights into the molecular underpinnings of various conditions. Our company, with its extensive background in genetic engineering and biological reagents, ensures these cell lines are rigorously validated and tailored to meet the needs of cutting-edge research, positioning us as leaders in the field of functional genomics.

Please note that all services are for research use only. Not intended for any clinical use.

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