Gene: NT5C3B
Official Full Name: 5'-nucleotidase, cytosolic IIIBprovided by HGNC
Gene Summary: Predicted to enable 5'-nucleotidase activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30654 | NT5C3B Knockout cell line (HeLa) | Human | NT5C3B | 1:3~1:6 | Negative | Online Inquiry |
KO30655 | NT5C3B Knockout cell line (HCT 116) | Human | NT5C3B | 1:2~1:4 | Negative | Online Inquiry |
KO30656 | NT5C3B Knockout cell line (HEK293) | Human | NT5C3B | 1:3~1:6 | Negative | Online Inquiry |
KO30657 | NT5C3B Knockout cell line (A549) | Human | NT5C3B | 1:3~1:4 | Negative | Online Inquiry |
NT5C3B Gene Knockout Cell Lines are a specialized biological product designed to facilitate advanced research into the roles of the NT5C3B gene and its associated pathways in various cellular processes. These cell lines have been engineered using CRISPR-Cas9 technology to create precise deletions in the NT5C3B gene, allowing researchers to assess the consequences of gene loss on cellular functions and metabolic pathways.
The primary function of NT5C3B Gene Knockout Cell Lines is to serve as models for studying the enzymatic activity and biological significance of the NT5C3B protein, which is crucial in nucleotide metabolism and immune response modulation. By examining the phenotypic and biochemical changes in these knockout lines, researchers can elucidate the gene's role in conditions such as cancer, autoimmune disorders, and cardiovascular diseases. The modified cell lines allow for detailed investigation into changes in cell proliferation, apoptosis, and response to treatment, providing critical insights into therapeutic targeting.
Scientifically, NT5C3B's implications are profound; these knockout cell lines can contribute to clinical research, drug development, and personalized medicine. The ability to explore gene function in vitro significantly enhances translational research, facilitating the identification of biomarkers and novel therapeutic strategies.
Compared to traditional methods of gene silencing, such as RNA interference, our NT5C3B knockout cell lines offer a more permanent and stable alteration of gene expression. This stability is paramount for long-term studies and reproducibility, reducing variability seen in transient knockdown approaches. Additionally, the high specificity of CRISPR-Cas9 ensures minimized off-target effects, thereby enhancing experimental accuracy.
The value of NT5C3B Gene Knockout Cell Lines lies in their capacity to accelerate discoveries in molecular biology and medicine, offering researchers and clinicians highly relevant models to better understand disease mechanisms and therapeutic interventions. Our company prides itself on its commitment to quality and innovation, backed by a team of experts in genetic engineering and molecular biology, ensuring that our product meets the highest standards for research use. Through our offerings, we empower the scientific community to push the boundaries of discovery and enhance the development of novel treatments.
Please note that all services are for research use only. Not intended for any clinical use.
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