Gene: NOA1
Official Full Name: nitric oxide associated 1provided by HGNC
Gene Summary: The protein encoded by this gene is a nuclear-encoded GTPase that functions in the mitochondrion. Upon translation, this protein is imported into the nucleus and then into the nucleolus before being exported to the mitochondrion. The encoded protein is required for oxygen-dependent regulation of mitochondrial respiratory complexes and for mitochondrial protein synthesis. [provided by RefSeq, Dec 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24998 | NOA1 Knockout cell line (HeLa) | Human | NOA1 | 1:3~1:6 | Negative | Online Inquiry |
KO24999 | NOA1 Knockout cell line (HCT 116) | Human | NOA1 | 1:2~1:4 | Negative | Online Inquiry |
KO25000 | NOA1 Knockout cell line (HEK293) | Human | NOA1 | 1:3~1:6 | Negative | Online Inquiry |
KO25001 | NOA1 Knockout cell line (A549) | Human | NOA1 | 1:3~1:4 | Negative | Online Inquiry |
NOA1 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research and therapeutic development, specifically designed to help scientists elucidate the functional roles of the NOA1 gene in various biological pathways. These cell lines are genetically engineered to have the NOA1 gene completely disrupted, enabling researchers to study the consequences of its absence on cellular behavior, signaling pathways, and overall physiology.
The primary function of the NOA1 gene involves the regulation of nitric oxide synthesis and mitochondrial function, both of which are critical for cellular metabolism and signaling. By utilizing these knockout cell lines, scientists can investigate how the absence of NOA1 affects aspects such as oxidative stress response, apoptosis, and cellular proliferation. This understanding is pivotal, especially in the context of diseases where NOA1 may play a role, such as cancer or neurodegenerative disorders.
In research and clinical laboratories, the NOA1 Gene Knockout Cell Lines hold significant importance for their applications in drug development and disease modeling. Researchers can utilize these models to identify potential therapeutic targets or biomarkers associated with NOA1-related pathologies. Furthermore, the utility of these cell lines extends to high-throughput screening, enabling the rapid evaluation of compounds that may modulate the effects of NOA1 in disease contexts.
What sets our NOA1 Gene Knockout Cell Lines apart from alternatives is their robust and validated genetic modification, coupled with comprehensive characterization data that support reproducibility and reliability in experiments. Additionally, unlike many other knockout models, our product is developed through rigorous methodologies that ensure minimal off-target effects and maintain stable phenotype over passages.
For researchers, clinicians, and pharmaceutical companies, these cell lines are invaluable assets that streamline the exploration of NOA1's biological functions and its implications in health and disease. By providing an effective means to study gene function in a controlled environment, they accelerate the path from molecular discovery to clinical application.
At [Your Company Name], we pride ourselves on our commitment to advancing scientific inquiry through quality biological products. Our extensive experience in genetic engineering and cell line development guarantees that our offerings, including the NOA1 Gene Knockout Cell Lines, are of the utmost standard, facilitating your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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