Gene: NMU
Official Full Name: neuromedin Uprovided by HGNC
Gene Summary: This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31446 | NMU Knockout cell line (HeLa) | Human | NMU | 1:3~1:6 | Negative | Online Inquiry |
KO31447 | NMU Knockout cell line (HCT 116) | Human | NMU | 1:2~1:4 | Negative | Online Inquiry |
KO31448 | NMU Knockout cell line (HEK293) | Human | NMU | 1:3~1:6 | Negative | Online Inquiry |
NMU Gene Knockout Cell Lines are genetically modified cell lines specifically designed to silence the expression of the neuropeptide neuromedin U (NMU). This innovative product serves as a critical tool for researchers engaged in investigations of metabolic regulation, reproductive biology, and the overall impact of neuropeptides on physiological processes. The gene knockout mechanism operates via CRISPR/Cas9 technology, where the target gene is disrupted, resulting in the loss of NMU expression. This precise modification allows for the exploration of NMU's role across various biological pathways and its implications in diseases such as obesity, cancer, and stress-related disorders.
The scientific importance of NMU Gene Knockout Cell Lines lies in their ability to provide insights into NMU-related signaling pathways, enhancing our understanding of complex biological interactions. In both research and clinical settings, these cell lines facilitate the study of NMU's influence on cellular responses, offering a platform for drug discovery and development that targets neuropeptide-related pathways.
One of the key advantages of NMU Gene Knockout Cell Lines compared to alternative models is their specificity and reliability. These cell lines are rigorously validated for effective gene disruption, ensuring consistent results that can be reproduced across experiments. Additionally, our commitment to high-quality standards means that researchers can trust these models to yield biologically relevant findings.
For researchers and clinicians alike, NMU Gene Knockout Cell Lines represent a valuable asset in advancing the understanding of neuropeptide functions. Our expertise in genetic engineering allows us to offer cutting-edge products that meet the diverse needs of the scientific community, empowering professionals to uncover new therapeutic avenues and improve health outcomes. By choosing our NMU Gene Knockout Cell Lines, users gain access to innovative tools that push the boundaries of current biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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