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NAT14 Knockout Cell Lines

Gene: NAT14

Official Full Name: N-acetyltransferase 14 (putative)provided by HGNC

Gene Summary: Predicted to enable N-acetyltransferase activity. Predicted to be involved in DNA-templated transcription initiation and positive regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15867 NAT14 Knockout cell line (HeLa) Human NAT14 1:3~1:6 Negative Online Inquiry
KO15868 NAT14 Knockout cell line (HCT 116) Human NAT14 1:2~1:4 Negative Online Inquiry
KO15869 NAT14 Knockout cell line (HEK293) Human NAT14 1:3~1:6 Negative Online Inquiry
KO15870 NAT14 Knockout cell line (A549) Human NAT14 1:3~1:4 Negative Online Inquiry

Background

NAT14 Gene Knockout Cell Lines are genetically engineered products designed to facilitate the study of NAT14 function by creating a cellular model lacking the NAT14 gene. This innovative product is invaluable for investigational research, allowing scientists to dissect the role of NAT14 in various biological processes, including gene expression regulation, cellular metabolism, and response to stressors. By utilizing CRISPR-Cas9 technology, these cell lines ensure precise and reliable gene editing, leading to consistent knockout efficiencies.

The primary mechanism of action of NAT14 Gene Knockout Cell Lines lies in the targeted repression of NAT14, a non-coding RNA implicated in various pathologies, including cancer and metabolic disorders. By removing this gene, researchers can observe the downstream effects on cellular morphology, division, and gene expression, providing significant insights into NAT14's contributions to signal transduction pathways.

The scientific importance of these cell lines extends to their applications in both basic and translational research. They serve as potent tools to investigate the molecular mechanisms underlying diseases and to assess the efficacy of therapeutic interventions aimed at modulating NAT14 activity. Compared to conventional knockdown approaches, which can produce variable results due to the incomplete silencing of target genes, the complete knockout achieved through these cell lines offers unparalleled clarity and reliability in experimental outcomes.

Researchers, clinicians, and pharmaceutical developers benefit from the precise and predictable nature of NAT14 Gene Knockout Cell Lines, making them valuable assets for high-throughput screening applications and validation of novel drug targets. The ability to generate reproducible data accelerates the development of therapeutic strategies, while the accessibility of this tool enriches the current knowledge base in molecular biology and genetics.

At our company, we pride ourselves on delivering high-quality biological products backed by rigorous scientific research and a commitment to innovation. Our expertise in gene editing technologies guarantees that researchers have access to reliable tools that drive scientific advancement and foster breakthroughs in understanding complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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