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N4BP3 Knockout Cell Lines

Gene: N4BP3

Official Full Name: NEDD4 binding protein 3provided by HGNC

Gene Summary: Acts upstream of with a positive effect on innate immune response. Predicted to be located in axon and dendrite. Predicted to be active in cytoplasmic vesicle. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29812 N4BP3 Knockout cell line (HCT 116) Human N4BP3 1:2~1:4 Negative Online Inquiry
KO29813 N4BP3 Knockout cell line (HEK293) Human N4BP3 1:3~1:6 Negative Online Inquiry

Background

N4BP3 Gene Knockout Cell Lines are specifically engineered cellular models that enable the study of the N4BP3 gene and its associated pathways by creating a complete gene disruption. This model utilizes CRISPR/Cas9 technology to facilitate precise genome editing, allowing researchers to understand the functional roles of N4BP3 in various biological processes, including cell proliferation, apoptosis, and immune response modulation.

The core mechanism of N4BP3 Gene Knockout Cell Lines lies in the targeted biogenesis of genetic mutations that hinder the expression of the N4BP3 gene. By disrupting the coding sequence of this gene, the resulting cell lines provide a powerful tool to investigate downstream signaling cascades and phenotypic changes in cellular behavior, offering insights into N4BP3’s involvement in diseases such as cancer and inflammatory disorders.

The scientific significance of these knockout models extends to both research and clinical applications. They are invaluable for elucidating gene function, screening potential therapeutic compounds, and assessing the efficacy of gene-targeted therapies. Researchers can leverage these cell lines in high-throughput screening assays or pathway analyses, contributing to the advancement of personalized medicine approaches and therapeutic strategies aimed at diseases linked to N4BP3 dysregulation.

One distinct advantage of N4BP3 Gene Knockout Cell Lines compared to traditional gene inhibition methods, like siRNA or shRNA, is the stable gene knockout, which offers a more robust and reproducible model for long-term studies. This leads to enhanced reliability in experimental outcomes and a deeper understanding of the gene's role in various biological contexts.

For researchers and clinicians working in genetics and cancer biology, the N4BP3 Gene Knockout Cell Lines are essential tools that aid in pushing the boundaries of scientific discovery. The capability to investigate gene functions at a molecular level empowers scientists to innovate and translate findings into clinical practice more effectively.

Our company is dedicated to providing high-quality genetic tools and cell lines, backed by extensive expertise in molecular biology. With a focus on precision and reliability, our products equip researchers to achieve groundbreaking results in their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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