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MYO15B Knockout Cell Lines

Gene: MYO15B

Official Full Name: myosin XVBprovided by HGNC

Gene Summary: Predicted to enable ATP binding activity; actin binding activity; and cytoskeletal motor activity. Predicted to be located in brush border; cytoplasm; and cytoskeleton. Predicted to be part of myosin complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26284 MYO15B Knockout cell line (HeLa) Human MYO15B 1:3~1:6 Negative Online Inquiry
KO26285 MYO15B Knockout cell line (HCT 116) Human MYO15B 1:2~1:4 Negative Online Inquiry
KO26286 MYO15B Knockout cell line (HEK293) Human MYO15B 1:3~1:6 Negative Online Inquiry
KO26287 MYO15B Knockout cell line (A549) Human MYO15B 1:3~1:4 Negative Online Inquiry

Background

MYO15B Gene Knockout Cell Lines are specifically engineered cellular models designed to study the MYO15B gene's role in various biological processes, particularly auditory functions and associated disorders. This product comprises a population of cells wherein the MYO15B gene has been systematically inactivated using precise genomic editing techniques, such as CRISPR-Cas9. By effectively disrupting the gene's function, these cell lines serve as invaluable tools for investigating the underlying molecular mechanisms of hearing loss and for performing drug discovery and genetic function studies.

The core mechanism of the MYO15B Gene Knockout Cell Lines lies in their capacity to enable researchers to observe phenotypic changes resulting from the absence of MYO15B. This gene is instrumental in hair cell development and function in the inner ear, and its disruption leads to cellular responses that mimic aspects of genetic hearing loss. These observations not only pave the way for understanding auditory pathology but also assist in exploring potential therapeutic interventions aimed at restoring hearing.

Scientifically, these cell lines are crucial in both research and clinical settings. They allow for the testing of hypotheses surrounding genetic diseases and facilitate the discovery of novel biomolecular pathways involved in hearing. Furthermore, they stand to impact translational medicine by providing insights that may lead to new treatment paradigms for sensorineural hearing loss.

Compared to conventional cell lines, MYO15B Gene Knockout Cell Lines offer a targeted approach that minimizes extraneous variability associated with gene expression, thus providing a more straightforward interpretation of experimental results. They are tailored for specificity, which enhances experimental reproducibility and reliability, key metrics in scientific research.

For researchers, clinicians, and biotechnology professionals aiming to unravel the complexities of genetic functions, MYO15B Gene Knockout Cell Lines represent a pivotal resource. They are not only a testament to the advancements in genetic engineering but also a critical asset for advancing our understanding of auditory functions. As a company dedicated to biotechnological innovation, we pride ourselves on producing high-quality, precisely engineered cell lines, ensuring that we contribute meaningfully to the scientific community's endeavors in genetic research and therapy development.

Please note that all services are for research use only. Not intended for any clinical use.

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