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MYO10 Knockout Cell Lines

Gene: MYO10

Official Full Name: myosin Xprovided by HGNC

Gene Summary: This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36488 MYO10 Knockout cell line (HeLa) Human MYO10 1:3~1:6 Negative Online Inquiry
KO36489 MYO10 Knockout cell line (HCT 116) Human MYO10 1:2~1:4 Negative Online Inquiry
KO36490 MYO10 Knockout cell line (HEK293) Human MYO10 1:3~1:6 Negative Online Inquiry
KO36491 MYO10 Knockout cell line (A549) Human MYO10 1:3~1:4 Negative Online Inquiry

Background

MYO10 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the MYO10 gene, which encodes for myosin X, a motor protein involved in cellular processes such as cell migration, adhesion, and intracellular transport. The deliberate disruption of this gene allows researchers to investigate the role of myosin X in various physiological and pathological contexts, providing valuable insights into its functions in cellular dynamics and signaling pathways.

These cell lines function by utilizing targeted gene editing techniques, such as CRISPR-Cas9, to achieve precise knockouts of the MYO10 gene. The absence of myosin X facilitates the study of its contributions to cytoskeletal organization, vesicular trafficking, and cell morphology — critical for understanding diseases like cancer, where cell migration and invasion are key factors. In addition, these knockout lines serve as essential tools for drug discovery, enabling the identification of compounds that target specific pathways altered by the absence of MYO10.

The scientific importance of MYO10 Gene Knockout Cell Lines extends to a variety of research fields, including cell biology, pharmacology, and neurobiology. These models can be employed in regenerative medicine, cancer research, and studies related to chronic inflammatory diseases, making them invaluable for both academic and clinical investigations. Compared to traditional knockout models, MYO10 Gene Knockout Cell Lines offer enhanced specificity and reduced variability, providing researchers with more reproducible results.

The unique selling points of these cell lines include ease of use, the ability to generate multiple clones with consistent knockout efficiency, and the comprehensive support provided for their application. Researchers can rely on these engineered cells to yield significant data while minimizing the time and resources typically required in gene knockout studies.

In conclusion, MYO10 Gene Knockout Cell Lines represent a pivotal advancement for those investigating cell mechanics and signaling pathways. As a leader in innovative biological products, our company is committed to empowering researchers and clinicians with high-quality tools that unlock new biological insights and improve health outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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