Gene: MYH10
Official Full Name: myosin heavy chain 10provided by HGNC
Gene Summary: This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05010 | MYH10 Knockout cell line (HeLa) | Human | MYH10 | 1:3~1:6 | Negative | Online Inquiry |
KO05011 | MYH10 Knockout cell line (HCT 116) | Human | MYH10 | 1:2~1:4 | Negative | Online Inquiry |
KO05012 | MYH10 Knockout cell line (HEK293) | Human | MYH10 | 1:3~1:6 | Negative | Online Inquiry |
KO05013 | MYH10 Knockout cell line (A549) | Human | MYH10 | 1:3~1:4 | Negative | Online Inquiry |
MYH10 Gene Knockout Cell Lines are precision-engineered cellular models designed to study the functional implications of the MYH10 gene, which encodes the protein Myosin II (non-muscle). This gene plays a pivotal role in various cellular processes, including motility, division, and muscle contraction. By utilizing CRISPR-Cas9 technology, these knockout cell lines exhibit loss of MYH10 expression, providing a valuable tool for elucidating the gene’s biological pathways and mechanisms.
The key function of MYH10 Gene Knockout Cell Lines lies in their ability to facilitate in-depth investigations into the role of MYH10 in cellular dynamics. Researchers can utilize these cell lines to analyze alterations in cytoskeletal organization, cell adhesion, and migration patterns, focusing on how MYH10 affects cellular behavior under physiological and pathological conditions. The knockout model is instrumental for dissecting the molecular pathways associated with diseases such as cancer and cardiovascular disorders where abnormal cell movement is a hallmark.
In research and clinical settings, these cell lines are vital for developing targeted therapies and drug screening assays. The ability to study MYH10 in a controlled environment allows for the identification of potential therapeutic targets and biomarkers. Unlike conventional cell lines, which may retain varying levels of MYH10 expression, our knockout lines ensure consistent and reproducible results, making them more reliable for experimental applications.
The MYH10 Gene Knockout Cell Lines distinguish themselves through their rigorous validation and the specificity of the gene editing process. This precise targeting mitigates off-target effects, enhancing data integrity compared to alternatives that may present confounding variables. Furthermore, their user-friendly protocols enable swift integration into existing research workflows, minimizing downtime and maximizing efficiency.
For researchers and clinicians, the availability of MYH10 Gene Knockout Cell Lines represents a strategic asset for advancing the understanding of cellular mechanics and developing innovative therapeutic approaches. These cell lines not only promote pioneering research but also pave the way for clinical advancements aimed at tackling complex diseases.
Our company embodies extensive expertise in genetic engineering and cell line development, ensuring that we deliver high-quality, expertly crafted biological tools to support the scientific community in its quest for knowledge and therapeutic solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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