Gene: MXRA7
Official Full Name: matrix remodeling associated 7provided by HGNC
Gene Summary: Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21596 | MXRA7 Knockout cell line (HeLa) | Human | MXRA7 | 1:3~1:6 | Negative | Online Inquiry |
KO21597 | MXRA7 Knockout cell line (HCT 116) | Human | MXRA7 | 1:2~1:4 | Negative | Online Inquiry |
KO21598 | MXRA7 Knockout cell line (HEK293) | Human | MXRA7 | 1:3~1:6 | Negative | Online Inquiry |
KO21599 | MXRA7 Knockout cell line (A549) | Human | MXRA7 | 1:3~1:4 | Negative | Online Inquiry |
MXRA7 Gene Knockout Cell Lines are genetically engineered cellular models that enable researchers to study the effects of targeted gene disruption on various biological processes. The MXRA7 gene, which encodes a membrane-associated protein implicated in cell adhesion and signaling, plays a significant role in modulating immune responses and the extracellular matrix's composition. By utilizing CRISPR/Cas9 technology, these knockout cell lines are created to specifically disrupt the MXRA7 gene, allowing for an in-depth analysis of its functions in different cellular contexts.
These knockout cell lines operate on the principle of gene editing, wherein the targeted alteration of the MXRA7 DNA sequence leads to a loss-of-function phenotype. As a result, researchers can investigate the downstream effects of MXRA7 deletion on cell behavior, including proliferation, differentiation, and response to external stimuli. This specificity in understanding gene function is essential for advancing knowledge in areas such as immunology, cancer research, and regenerative medicine.
The scientific importance of MXRA7 Gene Knockout Cell Lines is underscored by their ability to provide a controlled environment for examining gene interactions and pathways. These models facilitate the exploration of potential therapeutic targets and the development of innovative treatments. In clinical settings, understanding MXRA7's role could inform strategies for treating diseases characterized by dysfunctional immune response or altered extracellular matrix dynamics.
What sets MXRA7 Gene Knockout Cell Lines apart from alternative models is their precision and relevance. While traditional knockdown methods, such as RNA interference, may yield incomplete or transient effects, CRISPR/Cas9-mediated knockout provides a permanent modification that ensures consistent results across studies. Additionally, the availability of these cell lines promotes reproducibility and accelerates the research timeline, making them an indispensable resource for scientists.
For researchers and clinicians alike, possessing high-quality gene knockout models unlocks new avenues for exploration and potential application. These cell lines not only enhance fundamental research but also lay the groundwork for future breakthroughs in therapeutic interventions. Our company is committed to advancing biological research by providing innovative and reliable genetic tools, ensuring that researchers have the resources necessary to achieve their scientific objectives.
Please note that all services are for research use only. Not intended for any clinical use.
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