Gene: MUC13
Official Full Name: mucin 13, cell surface associatedprovided by HGNC
Gene Summary: Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20453 | MUC13 Knockout cell line (A549) | Human | MUC13 | 1:3~1:4 | Negative | Online Inquiry |
MUC13 Gene Knockout Cell Lines represent a groundbreaking advancement in the field of molecular biology, specifically in the study of cancer and epithelial biology. These specialized cell lines are engineered to lack the expression of the MUC13 gene, a member of the mucin family known for its role in cellular signaling, adhesion, and the promotion of tumor progression. By removing the MUC13 gene, researchers can effectively investigate its contributions to oncogenesis and other pathological conditions, offering insights into the molecular mechanisms driving disease.
The primary function of these knockout cell lines lies in their ability to elucidate the biological roles of MUC13 in various cellular processes, including cell proliferation, migration, and response to therapeutic agents. By utilizing these cell lines in experimental setups, researchers can assess the impact of MUC13 absence on signaling pathways and tumor microenvironment interactions, providing a more comprehensive understanding of its functions and potential as a therapeutic target.
The scientific significance of MUC13 Gene Knockout Cell Lines is underscored by their application in both fundamental research and clinical settings. These cell lines can facilitate drug discovery efforts targeting MUC13-related pathways in different cancers and can also serve as valuable models for studying epithelial disorders and the tumor immune microenvironment.
Compared to alternative models, MUC13 Gene Knockout Cell Lines offer the unique advantage of specificity and reproducibility, ensuring that experimental results are directly attributable to the manipulation of the MUC13 gene. This reduces variability and enhances the validity of research findings, making them indispensable tools for investigators seeking to unravel complex biological questions.
For researchers and clinicians, the value of MUC13 Gene Knockout Cell Lines extends beyond basic research; they represent powerful assets in developing targeted therapies and improving patient outcomes in cancer treatment. By utilizing these innovative cell lines, users can advance their research agenda with high confidence in the fidelity of their results.
Our company specializes in providing robust biological tools that empower the scientific community. With a commitment to quality and innovation, we are dedicated to supporting research endeavors that drive progress in health and disease understanding, ensuring that our product offerings meet the highest standards of excellence.
Please note that all services are for research use only. Not intended for any clinical use.
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