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MTUS1 Knockout Cell Lines

Gene: MTUS1

Official Full Name: microtubule associated scaffold protein 1provided by HGNC

Gene Summary: This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09649 MTUS1 Knockout cell line (HeLa) Human MTUS1 1:3~1:6 Negative Online Inquiry
KO09650 MTUS1 Knockout cell line (HCT 116) Human MTUS1 1:2~1:4 Negative Online Inquiry
KO09651 MTUS1 Knockout cell line (HEK293) Human MTUS1 1:3~1:6 Negative Online Inquiry
KO09652 MTUS1 Knockout cell line (A549) Human MTUS1 1:3~1:4 Negative Online Inquiry

Background

MTUS1 Gene Knockout Cell Lines represent a cutting-edge tool for molecular biology research, specifically designed to elucidate the functional properties of the MTUS1 gene. These cell lines are generated through the targeted deletion of the MTUS1 gene, allowing researchers to investigate the physiological and pathological roles of this gene in various biological processes. The mechanism of action involves CRISPR/Cas9 technology, which facilitates precise gene editing, offering a robust framework for assessing gene function, signaling pathways, and potential therapeutic targets.

The scientific importance of MTUS1 Gene Knockout Cell Lines is underscored by their applications in cancer research, cardiovascular studies, and cellular signaling investigations. By enabling the study of MTUS1's involvement in tumorigenesis and cell death, these cell lines contribute to a deeper understanding of disease mechanisms and may help identify novel biomolecular targets for therapeutic intervention. This can facilitate the development of innovative strategies in drug discovery and precision medicine.

What sets the MTUS1 Gene Knockout Cell Lines apart from alternative gene expression models is their specificity, reproducibility, and reliability. Unlike transient transfection methods, which can yield inconsistent results, these knockout models provide stable and physiological gene deficiencies. Additionally, their established background and characterization significantly reduce the variability often associated with new cell line development.

For researchers and clinicians, the MTUS1 Gene Knockout Cell Lines not only streamline experimental workflows but also enhance the reliability of experimental outcomes, fostering a more efficient path toward groundbreaking discoveries. With a focus on cutting-edge gene editing technologies, our company prides itself on delivering high-quality biological products that empower scientists to push the boundaries of current biomedical knowledge and application.

Please note that all services are for research use only. Not intended for any clinical use.

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