Home / MTMR9 Knockout Cell Lines

MTMR9 Knockout Cell Lines

Gene: MTMR9

Official Full Name: myotubularin related protein 9provided by HGNC

Gene Summary: This gene encodes a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SET interaction domain, which is thought to have a role in the control of cell proliferation. In mouse, a protein similar to the encoded protein binds with MTMR7, and together they dephosphorylate phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15973 MTMR9 Knockout cell line (HeLa) Human MTMR9 1:3~1:6 Negative Online Inquiry
KO15974 MTMR9 Knockout cell line (HCT 116) Human MTMR9 1:2~1:4 Negative Online Inquiry
KO15975 MTMR9 Knockout cell line (HEK293) Human MTMR9 1:3~1:6 Negative Online Inquiry
KO15976 MTMR9 Knockout cell line (A549) Human MTMR9 1:3~1:4 Negative Online Inquiry

Background

MTMR9 Gene Knockout Cell Lines are specifically engineered cellular models in which the MTMR9 gene has been inactivated, allowing for the exploration of the gene's role in cellular processes. MTMR9, part of the myotubularin family, is involved in lipid metabolism and signaling pathways, specifically regulating phosphatidylinositol-3-phosphate levels and influencing autophagy and insulin signaling. The knockout of MTMR9 enables researchers to study the downstream effects on cellular functions, providing insights into its contributions to various physiological and pathological conditions, including metabolic disorders and neurodegenerative diseases.

These knockout cell lines function through the complete absence of the MTMR9 gene, resulting in disrupted molecular pathways that can be quantitatively assessed. By comparing responses between wild-type and MTMR9 knockout cells, researchers can understand the gene's impact on cellular behavior, such as proliferation, apoptosis, and lipid handling. This detailed elucidation facilitates the investigation of therapeutic targets, especially in diseases where MTMR9 is implicated.

The scientific importance of MTMR9 Gene Knockout Cell Lines extends into multiple research fields, including endocrinology, neurology, and cancer biology. Their application in preclinical studies enhances our understanding of disease mechanisms and potential treatments.

One of the significant advantages of our MTMR9 knockout cell lines is the rigorous validation and characterization they undergo to ensure reproducibility and reliability for experimental use. Unlike traditional methods of gene silencing, such as RNA interference, knockout lines provide a complete loss of function, allowing for clearer interpretations of gene function. Furthermore, these models are essential for high-throughput screening assays to identify novel pharmacological agents targeting pathways modulated by MTMR9.

For researchers and clinicians, our MTMR9 Gene Knockout Cell Lines represent a critical tool for investigating complex biological phenomena and fostering advancements in therapeutic strategies. Our company prides itself on its expertise in cellular model development and its commitment to supplying high-quality, reliable products that meet the rigorous demands of scientific research. By choosing our knockout lines, users are ensuring they are working with the best resources available to elevate their research initiatives.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.