Gene: MSRA
Official Full Name: methionine sulfoxide reductase Aprovided by HGNC
Gene Summary: This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36554 | MSRA Knockout cell line (HeLa) | Human | MSRA | 1:3~1:6 | Negative | Online Inquiry |
KO36555 | MSRA Knockout cell line (HCT 116) | Human | MSRA | 1:2~1:4 | Negative | Online Inquiry |
KO36556 | MSRA Knockout cell line (A549) | Human | MSRA | 1:3~1:4 | Negative | Online Inquiry |
MSRA Gene Knockout Cell Lines represent a cutting-edge biological product designed for advanced research applications in genetic studies and molecular biology. These cell lines, which have undergone precise homologous recombination, effectively disable the methionine sulfoxide reductase A (MSRA) gene, a key player in cellular redox balance. By elucidating the role of MSRA in various physiological and pathological processes, researchers gain invaluable insights into oxidative stress responses and cellular signaling pathways.
The primary function of these knockout cell lines is to facilitate the study of the effects of MSRA deficiency in various cellular contexts. Mechanistically, the absence of the MSRA gene leads to an accumulation of methionine sulfoxide, resulting in altered cellular homeostasis and enhanced sensitivity to oxidative stress. This phenomenon proves pivotal in understanding the mechanisms underlying neurodegenerative diseases, cancer development, and other oxidative stress-related disorders.
Scientifically, MSRA Gene Knockout Cell Lines are indispensable tools for researchers investigating the implications of oxidative damage in cellular metabolism and signal transduction. Their application spans various fields, including pharmacology, toxicology, and the development of therapeutics, making them invaluable in both academic and clinical research settings.
Compared to conventional genetic manipulation methods, the specificity and reproducibility of our knockout cell lines offer a significant advantage, resulting in precise genetic modifications that enhance the reliability of experimental data. Our cell lines are rigorously validated for consistency, ensuring that researchers can trust their experimental results.
In summary, MSRA Gene Knockout Cell Lines provide an unprecedented opportunity for investigators to explore the intricate relationship between oxidative stress and cellular function. With our commitment to quality and innovation, our company stands at the forefront of biological research products, offering robust solutions that empower scientists and clinicians to transform their findings into impactful therapies and insights.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.