Gene: MSC
Official Full Name: musculinprovided by HGNC
Gene Summary: The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33425 | MSC Knockout cell line (A549) | Human | MSC | 1:3~1:4 | Negative | Online Inquiry |
MSC Gene Knockout Cell Lines are a cutting-edge suite of genetically engineered cell cultures specifically designed to facilitate the study of mesenchymal stem cells (MSCs) and their implications in regenerative medicine and disease modeling. These cell lines have undergone targeted editing to knock out specific genes of interest, enabling researchers to analyze the functional consequences of gene depletion and the associated biological pathways.
The key function of MSC Gene Knockout Cell Lines lies in their ability to reveal the roles of specific genes in cell proliferation, differentiation, and the healing processes of various tissues. By utilizing techniques such as CRISPR/Cas9 or homologous recombination, these cell lines provide a robust platform to dissect molecular mechanisms and cellular responses in controlled experimental settings, serving as invaluable tools for elucidating gene function and interaction.
The scientific importance of these cell lines is underscored by their broad applications in both research and clinical settings. They allow for the investigation of fundamental biological processes involved in bone and cartilage formation, wound healing, and immune responses, which are crucial for developing targeted therapies for conditions like osteoarthritis, osteoporosis, and other degenerative diseases.
Compared to conventional cell lines or unmodified MSCs, MSC Gene Knockout Cell Lines offer the unique advantage of precision gene editing, allowing for specific and reproducible modulation of gene expression without the complications introduced by off-target effects. This precision empowers researchers to develop more accurate disease models and therapeutic strategies, significantly enhancing the potential for translational research.
For researchers, clinicians, and biotechnology companies, the ability to utilize these knockout cell lines represents a gateway to innovative discoveries and advancements in the field of regenerative medicine. The reliability and specificity of these tools facilitate the acceleration of research timelines and improve the predictability of experimental outcomes.
Our company specializes in the development of state-of-the-art biological products, and our MSC Gene Knockout Cell Lines embody our commitment to providing researchers with high-quality, innovative tools that drive scientific advancement. With years of expertise in genetic engineering and stem cell technology, we are dedicated to supporting the next generation of biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.