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MRS2 Knockout Cell Lines

Gene: MRS2

Official Full Name: magnesium transporter MRS2provided by HGNC

Gene Summary: Enables magnesium ion transmembrane transporter activity. Involved in mitochondrial magnesium ion transmembrane transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16029 MRS2 Knockout cell line (HeLa) Human MRS2 1:3~1:6 Negative Online Inquiry
KO16030 MRS2 Knockout cell line (HCT 116) Human MRS2 1:2~1:4 Negative Online Inquiry
KO16031 MRS2 Knockout cell line (HEK293) Human MRS2 1:3~1:6 Negative Online Inquiry
KO16032 MRS2 Knockout cell line (A549) Human MRS2 1:3~1:4 Negative Online Inquiry

Background

MRS2 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the roles of the MRS2 gene, which encodes a magnesium transport protein critical for cellular function. By creating knockout versions of these cell lines, researchers can effectively observe the phenotypic consequences of MRS2 gene disruption, enabling the investigation of various biological processes, including metabolism, signaling pathways, and cellular stress responses.

These cell lines operate through the precise editing of the MRS2 gene, typically utilizing CRISPR/Cas9 technology to induce targeted mutations. The absence of functional MRS2 protein in these knockout cells allows for direct assessment of its involvement in magnesium homeostasis and other physiological processes within the cell. This controlled setting serves as a valuable tool for dissecting the gene’s contribution to diseases where magnesium dysregulation may play a role, such as cardiovascular disorders and neurodegenerative diseases.

Scientifically, MRS2 Gene Knockout Cell Lines are indispensable for research and clinical applications. They provide insights into the mechanistic role of magnesium in cellular functions and facilitate drug discovery targeting pathways related to MRS2, proving beneficial for both basic research and translational studies. These models enable the identification of novel therapeutic targets, thereby advancing our understanding and treatment of various diseases.

What sets MRS2 Gene Knockout Cell Lines apart from other models is their specificity and relevance. Unlike generic cell lines that may not accurately represent biological nuances, these knockouts are purposefully designed to eliminate MRS2 functionality, offering clarity in results and reproducibility in experiments. Researchers benefit from the ability to generate and screen therapeutic candidates effectively, thus accelerating the transition from laboratory findings to clinical applications.

The value proposition of MRS2 Gene Knockout Cell Lines is underscored by their potential to unlock new pathways in the study of magnesium transport and broader cellular functions, which aligns with the need for cutting-edge biological tools in modern research. Our company prides itself on delivering high-quality biological products backed by significant expertise in genetic engineering and cell line development. We are committed to supporting scientific endeavors that push the boundaries of knowledge and clinical innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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