Gene: MPLKIP
Official Full Name: M-phase specific PLK1 interacting proteinprovided by HGNC
Gene Summary: The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy. [provided by RefSeq, Nov 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04023 | MPLKIP Knockout cell line (HeLa) | Human | MPLKIP | 1:3~1:6 | Negative | Online Inquiry |
KO04024 | MPLKIP Knockout cell line (HCT 116) | Human | MPLKIP | 1:2~1:4 | Negative | Online Inquiry |
KO04025 | MPLKIP Knockout cell line (HEK293) | Human | MPLKIP | 1:3~1:6 | Negative | Online Inquiry |
KO04026 | MPLKIP Knockout cell line (A549) | Human | MPLKIP | 1:3~1:4 | Negative | Online Inquiry |
MPLKIP Gene Knockout Cell Lines are specialized cellular models that have undergone targeted genetic modification to disrupt the expression of the MPLKIP gene. This gene is implicated in crucial cellular pathways related to metabolism and signal transduction. By creating a knockout of MPLKIP, researchers can study the gene's function and its role in various biological processes, including cell growth, differentiation, and response to stress stimuli.
The key mechanism of action for the MPLKIP Gene Knockout Cell Lines lies in the selective disruption of gene function through approaches such as CRISPR-Cas9 or RNA interference, both of which utilize sophisticated biotechnological methods to achieve high specificity in gene targeting. This precision allows for the investigation of gene function in a controlled environment, enabling researchers to draw meaningful conclusions about the biological implications of MPLKIP in various contexts.
Scientifically, these knockout cell lines stand as valuable tools in both fundamental and applied research settings. They facilitate the elucidation of molecular pathways involved in diseases such as cancer and metabolic disorders, thereby illuminating potential therapeutic targets. In clinical research, they can be particularly useful for drug development, toxicity testing, and biomarker discovery, thus bridging the gap between laboratory findings and practical medical applications.
Compared to other cell lines, MPLKIP Gene Knockout Cell Lines offer unique advantages, including a higher fidelity in replicating in vivo conditions and a robust platform for studying the effects of gene loss. Furthermore, they present an excellent alternative to traditional overexpression systems, as the knockout model inherently captures the loss-of-function consequences, producing results that are often more representative of the biological reality.
For researchers and clinicians seeking to advance their understanding of gene function and its implications in health and disease, MPLKIP Gene Knockout Cell Lines provide a crucial resource. These cell lines empower users with the ability to explore complex biological networks with unprecedented accuracy.
Our company specializes in cutting-edge gene editing technologies and offers an array of biological products tailored for innovative research. With extensive expertise in cell line development and gene function analysis, we are committed to supporting the scientific community with high-quality tools that facilitate discovery and enhance the potential for groundbreaking clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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