Gene: MORF4L2
Official Full Name: mortality factor 4 like 2provided by HGNC
Gene Summary: Involved in positive regulation of double-strand break repair via homologous recombination and regulation of cell cycle. Located in nucleolus; nucleoplasm; and plasma membrane. Part of NuA4 histone acetyltransferase complex and nucleosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02347 | MORF4L2 Knockout cell line (HeLa) | Human | MORF4L2 | 1:3~1:6 | Negative | Online Inquiry |
KO02348 | MORF4L2 Knockout cell line (HCT 116) | Human | MORF4L2 | 1:2~1:4 | Negative | Online Inquiry |
KO02349 | MORF4L2 Knockout cell line (HEK293) | Human | MORF4L2 | 1:3~1:6 | Negative | Online Inquiry |
KO02350 | MORF4L2 Knockout cell line (A549) | Human | MORF4L2 | 1:3~1:4 | Negative | Online Inquiry |
MORF4L2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the MORF4L2 gene, which is implicated in various biological processes, including cellular proliferation, differentiation, and apoptosis. These knockout cell lines serve as valuable tools in molecular biology and genetic research, enabling scientists to dissect the functional roles of MORF4L2 in both normal physiology and pathological conditions, such as cancer. By studying these cell lines, researchers can elucidate the gene’s contribution to oncogenic signaling pathways, expanding our understanding of tumor biology and potentially uncovering new therapeutic targets.
The functionality of MORF4L2 knockout cell lines is grounded in the principles of gene editing, which typically employs techniques such as CRISPR-Cas9 or RNA interference to induce specific gene disruptions. This results in a phenotypic change that allows for high-throughput assays to assess morphogenetic consequences, migration, invasion, and treatment responses—activities critical for drug development and efficacy testing. Moreover, the loss of MORF4L2 can affect regulatory mechanisms involved in epigenetic modulation, providing a broad spectrum of research applications from cancer biology to regenerative medicine.
The scientific importance of these cell lines cannot be overstated. They lend themselves to applications in both basic and translational research, where understanding the fundamental roles of genes can lead to breakthroughs in the development of new treatment regimens and clinical approaches. By enabling researchers to model diseases more accurately, these knockout cell lines facilitate the translation of benchside discoveries to bedside solutions.
Compared to alternatives such as overexpressing the gene or using wild-type cells, MORF4L2 knockout cell lines present a clear advantage by providing a more straightforward approach to study loss-of-function effects. This specific disruption provides clarity in distinguishing the contributions of MORF4L2 from other related pathways, leading to more precise results and conclusions.
For researchers and clinicians seeking refined tools for genetic and pathological investigation, MORF4L2 Gene Knockout Cell Lines are invaluable. They offer streamlined methodologies for understanding complex gene functions and interactions in disease contexts, ultimately aiding in the innovation of targeted therapies. Our company prides itself on providing high-quality, rigorously validated biological products that cater to the evolving needs of the scientific community, ensuring that you have the best resources at your disposal for groundbreaking research.
Please note that all services are for research use only. Not intended for any clinical use.
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