Gene: MORC3
Official Full Name: MORC family CW-type zinc finger 3provided by HGNC
Gene Summary: This gene encodes a protein that localizes to the nuclear matrix and forms nuclear bodies via an ATP-dependent mechanism. The protein is predicted to have coiled-coil and zinc finger domains and has RNA binding activity. Alternative splicing produces multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29207 | MORC3 Knockout cell line (HeLa) | Human | MORC3 | 1:3~1:6 | Negative | Online Inquiry |
KO29208 | MORC3 Knockout cell line (HCT 116) | Human | MORC3 | 1:2~1:4 | Negative | Online Inquiry |
KO29209 | MORC3 Knockout cell line (HEK293) | Human | MORC3 | 1:3~1:6 | Negative | Online Inquiry |
KO29210 | MORC3 Knockout cell line (A549) | Human | MORC3 | 1:3~1:4 | Negative | Online Inquiry |
MORC3 Gene Knockout Cell Lines are specialized cellular models engineered to lack the MORC3 gene, a component implicated in various biological processes, including gene regulation and DNA repair. These knockout models are crucial for studying the functions of MORC3 and its role in disease mechanisms, particularly in cancer and immune responses. By utilizing CRISPR/Cas9 technology, the MORC3 gene is precisely disrupted, enabling researchers to investigate the consequences of its absence in cellular behavior, proliferation, and response to external stimuli.
The key function of MORC3 in gene expression regulation makes these knockout cell lines valuable for elucidating fundamental biological pathways. They enable researchers to delve into the molecular mechanisms behind cell signaling, differentiation, and stress responses. Additionally, MORC3 has been associated with epigenetic regulation and chromatin remodeling; thus, its knockout offers insights into how such processes influence cell fate and pathology.
In both research and clinical settings, these cell lines serve as powerful tools for drug discovery, functional genomics, and understanding disease pathology. They are particularly useful in cancer research, allowing for the examination of tumor biology and the development of targeted therapies. Compared to alternative models, MORC3 Gene Knockout Cell Lines provide a more accurate representation of the gene's functional dynamics, as they enable the study of its absence in a controlled environment, free from compensatory mechanisms that might obscure results in intact cellular contexts.
Researchers and clinicians will find exceptional value in these cell lines, as they enhance the understanding of MORC3-associated conditions and pave the way for innovative therapeutic strategies. Furthermore, our company specializes in developing high-quality biological products, ensuring that scholars can depend on our expertise and commitment to advancing scientific knowledge through robust and reliable research tools like the MORC3 Gene Knockout Cell Lines.
Please note that all services are for research use only. Not intended for any clinical use.
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