Gene: MON1A
Official Full Name: MON1 homolog A, secretory trafficking associatedprovided by HGNC
Gene Summary: Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in protein secretion. Predicted to act upstream of or within establishment of localization in cell; intracellular iron ion homeostasis; and protein transport. Part of Mon1-Ccz1 complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00525 | MON1A knockout cell line (A549) | Human | MON1A | 1:3~1:4 | Negative | Online Inquiry |
KO07355 | MON1A Knockout cell line (HeLa) | Human | MON1A | 1:3~1:6 | Negative | Online Inquiry |
KO07356 | MON1A Knockout cell line (HCT 116) | Human | MON1A | 1:2~1:4 | Negative | Online Inquiry |
KO07357 | MON1A Knockout cell line (HEK293) | Human | MON1A | 1:3~1:6 | Negative | Online Inquiry |
MON1A Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to eliminate the expression of the MON1A gene, which plays a critical role in various cellular processes, including membrane trafficking and endosomal dynamics. By utilizing advanced CRISPR/Cas9 technology, these cell lines allow researchers to efficiently study the downstream effects of MON1A gene disruption on cellular functions and pathways, enabling a deeper understanding of its contributions to health and disease states.
The primary function of MON1A Gene Knockout Cell Lines is to serve as a powerful tool for elucidating the mechanistic roles of the MON1A gene in cellular environments. By removing this gene’s expression, researchers can observe alterations in cellular behavior, including changes in endosomal maturation, vesicle trafficking, and overall cellular homeostasis. This knockdown can significantly aid in the investigation of related pathologies such as neurodegeneration and cancer, where MON1A pathways may be dysregulated.
The scientific importance of MON1A Gene Knockout Cell Lines is underscored by their broad applications in both fundamental research and clinical settings. They can be used to develop targeted therapies and drug discovery processes, where understanding the genetic underpinnings of diseases is essential for creating effective treatments. Furthermore, these cell lines provide a reliable model for studying interactions with drugs and investigating combinatorial therapies that target endosomal pathways.
Compared to traditional methods of gene knockout, MON1A Gene Knockout Cell Lines offer distinct advantages, including higher efficiency, precision, and reproducibility. The CRISPR-modified lines can provide researchers with more consistent results, decreasing variability often found in other gene-editing methods. Moreover, they are readily available for use, which streamlines experimental design and implementation.
For researchers, clinicians, and pharmaceutical developers focused on gene function and disease mechanisms, MON1A Gene Knockout Cell Lines present a valuable resource. Their unique ability to facilitate a deeper understanding of complex biological processes makes them indispensable in advancing both scientific inquiry and clinical applications.
As a leader in biotechnology innovation, our company is committed to providing high-quality biological products that empower researchers to explore and unlock the mysteries of genetics and cellular biology. Each MON1A Gene Knockout Cell Line is rigorously validated, ensuring reliability and consistency for all experimental needs.
Please note that all services are for research use only. Not intended for any clinical use.
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