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MNT Knockout Cell Lines

Gene: MNT

Official Full Name: MAX network transcriptional repressorprovided by HGNC

Gene Summary: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36595 MNT Knockout cell line (HeLa) Human MNT 1:3~1:6 Negative Online Inquiry
KO36596 MNT Knockout cell line (HCT 116) Human MNT 1:2~1:4 Negative Online Inquiry
KO36597 MNT Knockout cell line (HEK293) Human MNT 1:3~1:6 Negative Online Inquiry
KO36598 MNT Knockout cell line (A549) Human MNT 1:3~1:4 Negative Online Inquiry

Background

MNT Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to enable researchers to investigate the role of the MNT gene in various biological processes. By utilizing the CRISPR-Cas9 gene editing technology, these cell lines have been rendered deficient in the expression of the MNT gene, allowing for the study of its function in cellular proliferation, differentiation, and response to environmental stimuli. The knockout mechanism involves precise editing of the gene's sequence, leading to a loss-of-function phenotype that effectively models the absence of MNT activity in cellular contexts.

The scientific importance of MNT Gene Knockout Cell Lines cannot be overstated. They serve as crucial tools for understanding the intricate regulatory networks linked to MNT, which is implicated in various pathologies, including cancer and metabolic disorders. These cell lines facilitate a multitude of applications, such as functional genomics, drug screening, and the evaluation of gene-environment interactions in both basic research and translational studies.

One significant advantage of our MNT Gene Knockout Cell Lines is their high specificity and efficiency, which surpass many traditional knockout methods like RNA interference, as they provide a complete loss of gene expression rather than transient suppression. This specificity leads to more reliable results that can be critical for publication-worthy studies. Furthermore, our cell lines are rigorously validated for quality and consistency, making them a preferred choice for researchers focused on reproducibility in their experimental designs.

For researchers and clinicians seeking to deepen their understanding of gene function or explore therapeutic avenues linked to MNT, these knockout cell lines represent an invaluable resource. They are not just a product but a gateway to advancing scientific knowledge and potential clinical insights. Our company has years of experience in developing precision biological products, ensuring that each offering is backed by both scientific rigor and commitment to customer support. Invest in MNT Gene Knockout Cell Lines to enhance your research capabilities and contribute to groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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