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MN1 Knockout Cell Lines

Gene: MN1

Official Full Name: MN1 proto-oncogene, transcriptional regulatorprovided by HGNC

Gene Summary: Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36599 MN1 Knockout cell line (HeLa) Human MN1 1:3~1:6 Negative Online Inquiry
KO36600 MN1 Knockout cell line (HCT 116) Human MN1 1:2~1:4 Negative Online Inquiry
KO36601 MN1 Knockout cell line (HEK293) Human MN1 1:3~1:6 Negative Online Inquiry
KO36602 MN1 Knockout cell line (A549) Human MN1 1:3~1:4 Negative Online Inquiry

Background

MN1 Gene Knockout Cell Lines are genetically modified cellular models specifically designed to study the functional implications of the MN1 gene in various biological processes. These cell lines have been engineered through CRISPR-Cas9 technology to create a precise knockout of the MN1 gene, resulting in a system that allows researchers to explore the gene’s role in cellular functions such as proliferation, differentiation, and response to external stimuli. The knockout mechanism leads to the ablation of MN1 protein activity, establishing a robust framework to elucidate its contributions to oncogenic pathways and hematologic malignancies.

The scientific importance of MN1 Gene Knockout Cell Lines lies in their application in both research and clinical settings. They provide essential insights into the pathophysiology of diseases associated with aberrant MN1 expression, making these cell lines invaluable for drug discovery and development efforts. Researchers can utilize MN1 knockout models to assess the efficacy of targeted therapies, developing novel treatments tailored to specific genetic backgrounds associated with cancers.

Compared to traditional cell lines or other knockout models, MN1 Gene Knockout Cell Lines offer enhanced specificity and reliability due to their precise gene editing. This precision allows for more accurate modeling of human disease mechanisms, enabling researchers to draw meaningful conclusions with greater confidence. Furthermore, the ease of use and adaptability of these cell lines in standard laboratory protocols make them a practical choice for a wide range of experimental applications.

In summary, MN1 Gene Knockout Cell Lines represent a powerful tool for advancing our understanding of the MN1 gene's role in human health and disease. For researchers and clinicians striving to unlock new knowledge in cancer biology, these cell lines provide unparalleled advantages. Our company specializes in high-quality genetic models, ensuring that you receive not only innovative products but also expert support to enhance your research endeavors and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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