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MLYCD Knockout Cell Lines

Gene: MLYCD

Official Full Name: malonyl-CoA decarboxylaseprovided by HGNC

Gene Summary: The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07432 MLYCD Knockout cell line (HeLa) Human MLYCD 1:3~1:6 Negative Online Inquiry
KO07433 MLYCD Knockout cell line (HCT 116) Human MLYCD 1:2~1:4 Negative Online Inquiry
KO07434 MLYCD Knockout cell line (HEK293) Human MLYCD 1:3~1:6 Negative Online Inquiry
KO07435 MLYCD Knockout cell line (A549) Human MLYCD 1:3~1:4 Negative Online Inquiry

Background

MLYCD Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to provide researchers with a powerful tool for investigating the role of the MLYCD (malonyl-CoA decarboxylase) gene in various biological processes. These cell lines have been constructed using advanced CRISPR/Cas9 gene-editing technology, enabling precise targeted disruptions of the MLYCD gene, thereby facilitating the study of its function in metabolic pathways, particularly in lipid metabolism and cellular energy regulation.

The key function of the MLYCD Gene Knockout Cell Lines lies in their ability to mimic pathophysiological conditions by enabling researchers to examine the consequences of MLYCD deficiency. This feature allows for the probing of metabolic alterations, signaling cascades, and the relationship between MLYCD and obesity, diabetes, and cardiovascular diseases. The loss of MLYCD expression provides insights into malonyl-CoA metabolism, contributing to the understanding of fatty acid homeostasis and energy balance, making these cell lines invaluable for both basic and translational research.

Scientifically, MLYCD Gene Knockout Cell Lines hold significant implications for drug discovery and development, as they serve as models for screening potential therapeutic compounds aimed at metabolic disorders. Their utility in research can lead to novel hypotheses and therapeutic strategies, while also enhancing the understanding of MLYCD's role in disease mechanisms.

What sets MLYCD Gene Knockout Cell Lines apart from alternatives is their high specificity and efficiency in gene disruption, coupled with thorough validation to ensure consistent performance. Researchers benefit from the ability to conduct high-throughput assays and complex experimental designs, providing reliable data and facilitating reproducibility—a critical aspect in advancing scientific understanding and therapeutic innovations.

For researchers, clinicians, and pharmaceutical companies dedicated to probing the complexities of metabolic diseases, MLYCD Gene Knockout Cell Lines represent an essential addition to their toolkit. By utilizing these models, stakeholders can achieve more comprehensive insights and accelerate the journey from discovery to clinical application.

With a strong commitment to advancing biological research, our company offers these innovative cell lines, backed by a team of experts dedicated to providing high-quality products that empower research communities worldwide.

Please note that all services are for research use only. Not intended for any clinical use.

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