Gene: MILR1
Official Full Name: mast cell immunoglobulin like receptor 1provided by HGNC
Gene Summary: Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway; mast cell degranulation; and negative regulation of mast cell activation. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00291 | MILR1 Knockout cell line (THP-1) | Human | MILR1 | 1:2-1:4 | Negative | Online Inquiry |
KO20338 | MILR1 Knockout cell line (HCT 116) | Human | MILR1 | 1:2~1:4 | Negative | Online Inquiry |
KO20339 | MILR1 Knockout cell line (A549) | Human | MILR1 | 1:3~1:4 | Negative | Online Inquiry |
MILR1 Gene Knockout Cell Lines are innovative biological tools designed for the precise study of the immune response and associated signaling pathways through the targeted deletion of the MILR1 gene. This gene plays a crucial role in immune cell regulation and has implications in various pathological conditions, including autoimmune diseases and cancer. By utilizing CRISPR/Cas9 technology, these cell lines provide researchers with the ability to generate Milr1 deficient models that facilitate the in-depth examination of immune mechanisms and therapeutic interventions.
The primary function of MILR1 Gene Knockout Cell Lines lies in their capacity to unravel the specific role of the MILR1 protein in immune signaling. By studying these knockout cell lines, researchers can observe the resulting phenotypic changes in cellular behavior, including alterations in proliferation, differentiation, and cytokine secretion. This allows for the elucidation of MILR1's role in immune responses, making it a vital tool for developmental biology and therapeutic research.
The scientific importance of these cell lines is underscored by their diverse applications in both research and clinical settings. They enable the study of innate immunity in diseases such as cancer, where MILR1 may influence tumor microenvironments and affect treatment outcomes. Additionally, they can be pivotal in the discovery of potential therapeutic targets or biomarkers for diseases involving immune dysregulation.
Compared to other gene knockout systems, the MILR1 Gene Knockout Cell Lines stand out due to their high specificity and efficiency, attributed to the advanced CRISPR technology employed in their development. Moreover, they are validated for consistent performance, ensuring reproducible results across experiments. These features significantly enhance their utility in various laboratory settings.
For researchers and clinicians, the value of MILR1 Gene Knockout Cell Lines lies in their ability to foster groundbreaking discoveries in immunology and related fields, ultimately contributing to improved therapeutic strategies. With every experiment, these cell lines offer insights that can lead to significant advancements in understanding immune function and disease mechanisms.
Our company has a long-standing commitment to providing high-quality biological reagents and models, backed by extensive expertise in genetic engineering and cell biology. We strive to empower researchers with innovative tools that drive scientific discovery and clinical progress.
Please note that all services are for research use only. Not intended for any clinical use.
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