Home / MIER3 Knockout Cell Lines

MIER3 Knockout Cell Lines

Gene: MIER3

Official Full Name: MIER family member 3provided by HGNC

Gene Summary: Predicted to enable histone deacetylase binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of protein-containing complex. Implicated in breast cancer and lung adenocarcinoma. Biomarker of breast cancer; invasive ductal carcinoma; and lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16165 MIER3 Knockout cell line (HeLa) Human MIER3 1:3~1:6 Negative Online Inquiry
KO16166 MIER3 Knockout cell line (HCT 116) Human MIER3 1:2~1:4 Negative Online Inquiry
KO16167 MIER3 Knockout cell line (HEK293) Human MIER3 1:3~1:6 Negative Online Inquiry
KO16168 MIER3 Knockout cell line (A549) Human MIER3 1:3~1:4 Negative Online Inquiry

Background

MIER3 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology designed to facilitate advanced research into the MIER3 gene's functions and its implications in various biological processes. MIER3, a member of the MIER family, is known to play a significant role in transcriptional regulation, making its study crucial for understanding gene expression and cellular differentiation. These knockout cell lines have been meticulously engineered to disrupt the MIER3 gene, providing researchers with invaluable resources to study the gene's loss-of-function effects at the cellular and organismal levels.

The primary function of MIER3 Gene Knockout Cell Lines is to enable the exploration of MIER3's role in various physiological and pathological contexts, particularly in cancer and developmental biology. By utilizing these cell lines, researchers can elucidate the downstream signaling pathways affected by MIER3, assess its influence on cell proliferation, apoptosis, and differentiation, and provide insights into its contribution to oncogenesis. Furthermore, these knockout cell lines serve as a powerful platform for drug screening and therapeutic development, allowing for the identification of potential targets in diseases associated with aberrant MIER3 expression.

The scientific importance of MIER3 Gene Knockout Cell Lines extends beyond basic research; they play a pivotal role in translational medicine by aiding the discovery of novel biomarkers and therapeutic avenues. Compared to conventional methods, such as RNA interference or transgenic models, knockout cell lines offer a more stable and effective approach to studying gene function, leading to more replicable and reliable experimental outcomes. This makes them an indispensable resource for both academic and clinical laboratories.

What distinguishes MIER3 Gene Knockout Cell Lines from alternative products on the market is their high specificity and efficiency in gene editing. Crafted using cutting-edge CRISPR/Cas9 technology, these cell lines demonstrate minimal off-target effects, ensuring that observations are attributed directly to the MIER3 gene disruption. Additionally, our product line offers a range of knockout variants tailored for specific research needs, further enhancing experimental versatility.

For researchers and clinicians aiming to advance their understanding of gene function and develop innovative therapeutics, MIER3 Gene Knockout Cell Lines provide a robust, reliable, and scientifically enriched platform. By leveraging our expertise in cellular biology and genetic engineering, we proudly offer these knockout cell lines to support your research endeavors, ensuring you have access to the most effective tools in exploring the complexities of gene regulation and expression.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.