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MFAP3L Knockout Cell Lines

Gene: MFAP3L

Official Full Name: microfibril associated protein 3 likeprovided by HGNC

Gene Summary: Located in several cellular components, including cell junction; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32662 MFAP3L Knockout cell line (HeLa) Human MFAP3L 1:3~1:6 Negative Online Inquiry
KO32663 MFAP3L Knockout cell line (HCT 116) Human MFAP3L 1:2~1:4 Negative Online Inquiry
KO32664 MFAP3L Knockout cell line (HEK293) Human MFAP3L 1:3~1:6 Negative Online Inquiry
KO32665 MFAP3L Knockout cell line (A549) Human MFAP3L 1:3~1:4 Negative Online Inquiry

Background

MFAP3L Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the MFAP3L (Microfibril-Associated Protein 3-Like) gene. By employing advanced CRISPR-Cas9 gene editing technology, these cell lines facilitate a systematic investigation into the gene's functional roles in cellular processes such as cell adhesion, migration, and extracellular matrix interactions. The absence of MFAP3L allows researchers to elucidate the gene's contributions to various physiological and pathological conditions, including cardiovascular disease, tissue repair, and cancer metabolism.

The primary function of MFAP3L involves its association with microfibrils in the extracellular matrix, potentially influencing the mechanical properties of tissues and cellular behavior. Utilizing knockout cell lines enables scientists to study the phenotypic changes that occur in these cells in the absence of MFAP3L and to identify downstream signaling pathways that may be affected. This mechanism may be pivotal in understanding how altered gene expression impacts diseases related to connective tissues.

The scientific importance of MFAP3L Gene Knockout Cell Lines extends to their applications in basic molecular biology research as well as translational research in clinical settings. By providing a clear model for investigating gene function, these cell lines are invaluable for researchers studying the genetic basis of developmental disorders and chronic diseases. Their use in high-throughput screening can accelerate the discovery of novel therapeutic targets, supporting both academic and pharmaceutical research initiatives.

Compared to traditional methods of gene knockout, such as homologous recombination, our MFAP3L Gene Knockout Cell Lines offer several advantages, including reduced time for development, increased editing efficiency, and the ability to easily create a reproducible experimental model. Furthermore, these cell lines are rigorously characterized to ensure consistent results, making them a reliable choice for researchers.

For researchers, clinicians, and biotechnologists, investing in MFAP3L Gene Knockout Cell Lines translates into access to advanced tools that enhance understanding of gene function and disease mechanisms. With our company's deep expertise in cellular engineering and commitment to quality, we offer a reliable and innovative product that empowers our customers to push the boundaries of scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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