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METRNL Knockout Cell Lines

Gene: METRNL

Official Full Name: meteorin like, glial cell differentiation regulatorprovided by HGNC

Gene Summary: Predicted to enable hormone activity. Predicted to be involved in several processes, including brown fat cell differentiation; positive regulation of brown fat cell differentiation; and response to muscle activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16244 METRNL Knockout cell line (HeLa) Human METRNL 1:3~1:6 Negative Online Inquiry
KO16245 METRNL Knockout cell line (HCT 116) Human METRNL 1:2~1:4 Negative Online Inquiry
KO16246 METRNL Knockout cell line (HEK293) Human METRNL 1:3~1:6 Negative Online Inquiry
KO16247 METRNL Knockout cell line (A549) Human METRNL 1:3~1:4 Negative Online Inquiry

Background

METRNL Gene Knockout Cell Lines are genetically modified cellular models specifically designed to study the functional roles of the METRNL gene, which is implicated in various biological processes, including inflammation and metabolic regulation. These cell lines are generated through CRISPR-Cas9 technology, ensuring precise and reliable knockout of the METRNL gene, thereby allowing researchers to investigate the consequences of its absence on cellular behavior and function.

The key mechanisms underlying their utility involve the ability to elucidate the pathways linked to METRNL, offering insights into its involvement in pathophysiological conditions such as obesity and autoimmune disorders. Researchers can utilize these cell lines to assess alterations in cellular signaling, gene expression profiles, and metabolic processes, facilitating a better understanding of disease mechanisms.

The scientific importance of METRNL Gene Knockout Cell Lines lies in their potential applications in both fundamental and applied research. They serve as invaluable tools for developing therapeutic strategies and validating drug targets. In clinical settings, these models pave the way for discovering biomarkers that predict drug responses or disease outcomes.

What sets our METRNL Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility. Unlike commercially available cell lines that may harbor non-specific genetic variations, our knockout models are rigorously validated to confirm the absence of METRNL, ensuring experimental accuracy. Additionally, our dedicated support and comprehensive protocols facilitate seamless integration into your research workflow.

For researchers and clinicians venturing into the realms of gene function studies, disease modeling, and therapeutic discovery, METRNL Gene Knockout Cell Lines offer robust solutions that drive innovation. With a foundation built on cutting-edge technology and an experienced team, our company is committed to supporting the scientific community's quest for advancement in biological research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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